Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | MIF | P14174 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30730349 | 1.00 | NLRP3 (0.60) | NLRP3KDM4EALDH1A1GAAMAPK1 | |
| SCHEMBL17327742 | 0.84 | NLRP3 (0.60) | NLRP3KDM4EALDH1A1GAAMAPK1 | |
| SCHEMBL8889131 | 0.83 | NLRP3 (0.59) | NLRP3KDM4EALDH1A1GAAMAPK1 | |
| SCHEMBL27578457 | 0.81 | SIRT1 (0.64) | NLRP3KDM4EALDH1A1GAAMAPK1 | |
| SCHEMBL630523 | 0.81 | SIRT1 (0.64) | NLRP3KDM4EALDH1A1GAAMAPK1 | |
| SCHEMBL7809771 | 0.81 | NLRP3 (0.78) | NLRP3KDM4ELOXL2MTNR1AMTNR1B | |
| SCHEMBL3451201 | 0.81 | LOXL2 (0.58) | NLRP3KDM4EALDH1A1GAAMAPK1 | |
| SCHEMBL5462809 | 0.81 | NLRP3 (0.57) | NLRP3KDM4EALDH1A1GAAMAPK1 | |
| SCHEMBL12831379 | 0.80 | NLRP3 (0.48) | NLRP3KDM4EALDH1A1GAAMAPK1 | |
| SCHEMBL24852540 | 0.80 | KDM4E (0.59) | KDM4EALDH1A1GAAMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0967484-B1 | METHODS FOR DETECTING OR ASSAYING VIRUS | ADVANCED LIFE SCIENCE INST INC (JP) | 2007-05-02 | — | — | EP | claimed |
| CN-114176073-A | Surface-modifiable nanogel pesticide carrier and construction method thereof | 西南大学 | 2022-03-15 | — | — | CN | disclosed |