SCHEMBL630523

SCHEMBL630523

NC(=O)Cc1cc2ccccc2[nH]1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT1 Q96EB6 1/20 0.64
LOXL2 Q9Y4K0 1/20 0.59
NLRP3 Q96P20 1/20 0.54
MTNR1A P48039 1/20 0.53
MTNR1B P49286 1/20 0.53
KDM4E B2RXH2 3/20 0.51
ALDH1A1 P00352 2/20 0.51
GAA P10253 1/20 0.51
MAPK1 P28482 1/20 0.51
FLT3 P36888 1/20 0.50
IDO1 P14902 1/20 0.49
DAO P14920 2/20 0.49
MAPT P10636 1/20 0.49
HPGD P15428 1/20 0.49
SRD5A2 P31213 1/20 0.49
HSD17B10 Q99714 1/20 0.49
AOC3 Q16853 2/20 0.46
GSK3B P49841 1/20 0.45
HDAC3 O15379 1/20 0.45
HDAC1 Q13547 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27578457 1.00 SIRT1 (0.64) SIRT1LOXL2NLRP3MTNR1AMTNR1B
SCHEMBL3451201 0.85 LOXL2 (0.58) SIRT1LOXL2NLRP3MTNR1AMTNR1B
SCHEMBL29365671 0.84 LOXL2 (0.56) LOXL2NLRP3MTNR1AMTNR1BKDM4E
SCHEMBL49270 0.84 LOXL2 (0.56) LOXL2NLRP3MTNR1AMTNR1BKDM4E
SCHEMBL31336079 0.84 LOXL2 (0.56) LOXL2NLRP3MTNR1AMTNR1BKDM4E
SCHEMBL1381253 0.83 LOXL2 (0.53) SIRT1LOXL2NLRP3MTNR1AMTNR1B
SCHEMBL664282 0.83 MTNR1A (0.57) SIRT1LOXL2NLRP3MTNR1AMTNR1B
SCHEMBL30052135 0.83 MTNR1A (0.57) SIRT1LOXL2NLRP3MTNR1AMTNR1B
SCHEMBL8928685 0.82 LOXL2 (0.55) SIRT1LOXL2NLRP3MTNR1AMTNR1B
SCHEMBL3120573 0.82 MTNR1A (0.60) LOXL2NLRP3MTNR1AMTNR1BKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 279 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119709703-A Amide hydrolase mutant and application thereof 中国农业科学院植物保护研究所 2025-03-28 CN claimed
CN-119143455-B Anti-cracking concrete and preparation method thereof 廊坊泉泽混凝土有限公司 2025-02-11 CN claimed
CN-119320777-A Metabolite screening method for promoting expression of porcine intestinal defensin pBD1 and application thereof 浙江大学 2025-01-17 CN claimed
CN-119143455-A Anti-cracking concrete and preparation method thereof 廊坊泉泽混凝土有限公司 2024-12-17 CN claimed
WO-2024187115-A2 PRODUCTION OF INDOLE-DERIVED METABOLITES BY SHELF-STABLE COMMUNITIES OF SAFE BACTERIA Imvela Corp. (US) 2024-09-12 WO claimed
CN-118421724-A Application of tryptophan 2-monooxygenase and indoleacetamide dehydrogenase from microorganisms 浙江工业大学 2024-08-02 CN claimed
CN-117099601-A Special nursing method for burnt She Yinbai maple and burnt ginkgo 北京京彩弘景生态建设有限公司 2023-11-24 CN claimed
CN-114438138-A Metabolic composition prepared from clostridium sporogenes, and production method, detection method and application thereof 重庆市畜牧科学院 2022-05-06 CN claimed
CN-109705103-A The method for continuously preparing 3,4- (1- Methvl-indole -3- base) -1H- pyrroles's -2,5- ketone compounds 浙江工业大学 2019-05-03 CN claimed
EP-2279450-B1 ELECTROLYTES FOR ELECTROCHROMIC DEVICES CHROMOGENICS AB (SE) 2018-06-27 EP claimed
US-20060218658-A1 Novel selection method BASF PLANT SCIENCE GMBH (DE) 2006-09-28 US claimed
EP-0954596-B1 ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF TAXUS SPECIES PHYTON INC (US) 2006-01-04 EP claimed
EP-1538214-A1 Enhanced production of taxanes by cell cultures of taxus species PHYTON, INC. (US) 2005-06-08 EP claimed
US-20040163143-A1 Method for efficiently producing transgenic plant using auxin precursor NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2004-08-19 US claimed
CN-1473936-A Effectively producing transgene plant using auxin precursor �ձ���ֽ��ʽ���� 2004-02-11 CN claimed
EP-1384785-A1 Method for producing transgenic plant using an auxin synthesis gene as a positive selectable marker gene NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2004-01-28 EP claimed
EP-0954596-A1 ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF $i(TAXUS) SPECIES PHYTON, INC. (US) 1999-11-10 EP claimed
CN-1219201-A Genetic constructs and methods for producing small or seedless fruits PIONEER HI BRED INTERNATION IN (US) 1999-06-09 CN claimed
WO-1997044476-A1 ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF TAXUS SPECIES PHYTON, INC. (US) 1997-11-27 WO claimed
US-4868200-A LEUKOTRIENES, LIPOXYGENASE INHIBITORS WARNER-LAMBERT COMPANY (US) 1989-09-19 US claimed