Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 6/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | MTOR | P42345 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5976411 | 0.86 | PDE4D (0.35) | PDE4DPDE3ASLC29A1DNMT1ADRB1 | |
| SCHEMBL28114849 | 0.81 | DNMT1 (0.32) | DNMT1ADRB1 | |
| SCHEMBL28042109 | 0.79 | DNMT1 (0.50) | PDE4DPDE3ASLC29A1DNMT1ADRB1 | |
| SCHEMBL3038818 | 0.79 | PDE3A (0.52) | PDE4DPDE3ASLC29A1DNMT1ADRB1 | |
| SCHEMBL6394687 | 0.77 | RNASE1 (0.32) | DNMT1ADRB1ALDH1A1POLBHTT | |
| SCHEMBL29943756 | 0.77 | TK1 (0.43) | ALBLMNAALDH1A1POLBBLM | |
| SCHEMBL2294 | 0.77 | TK1 (0.43) | ALBLMNAALDH1A1POLBBLM | |
| SCHEMBL8581452 | 0.76 | DNMT1 (0.31) | DNMT1 | |
| SCHEMBL234386 | 0.75 | LMNA (0.34) | PDE4DPDE3ASLC29A1DNMT1ADRB1 | |
| SCHEMBL1684840 | 0.75 | DNMT1 (0.34) | PDE4DPDE3ASLC29A1DNMT1ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531452-A4 | SYNTHESIS OF GLYCEROL DI- AND TRIPHOSPHATE DERIVATIVES | — | 1993-06-09 | — | — | EP | disclosed |
| EP-0531452-A1 | SYNTHESIS OF GLYCEROL DI- AND TRIPHOSPHATE DERIVATIVES | NeXstar Pharmaceuticals, Inc. (US) | 1993-03-17 | — | — | EP | disclosed |
| WO-1991018914-A1 | SYNTHESIS OF GLYCEROL DI- AND TRIPHOSPHATE DERIVATIVES | VICAL, INC. (US) | 1991-12-12 | — | — | WO | disclosed |