SCHEMBL5501020

SCHEMBL5501020

C=CC[PH](CC=C)(CC=C)Cc1ccccc1C=C

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8019676 0.81 ALDH1A1 (0.38) ALDH1A1
SCHEMBL8035177 0.76 ALDH1A1 (0.40) ALDH1A1
SCHEMBL2344700 0.75 ALDH1A1 (0.33) ALDH1A1
SCHEMBL20567945 0.75 ALDH1A1 (0.33) ALDH1A1
Phosphine SCHEMBL8143769 0.74 ALDH1A1 (0.32) ALDH1A1
SCHEMBL1078488 0.73 ALDH1A1 (0.38) ALDH1A1
SCHEMBL2346267 0.73 THRA (0.37) ALDH1A1
SCHEMBL4835886 0.73 THRA (0.37) ALDH1A1
SCHEMBL4840342 0.73 THRA (0.37) ALDH1A1
SCHEMBL316855 0.73 ALDH1A1 (0.44) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0675968-B1 ENZYME-CATALYZED CHEMILUMINESCENT DETECTION OF PROTEINS AND NUCLEIC ACIDS USING HYDROXYARYL CYCLIC DIACYLHYDRAZIDE COMPOUNDS LUMIGEN INC (US) 2002-03-13 EP claimed
US-7300766-B2 Polymeric ammonium and or phosphonium salts having added π-electrons and higher molecular weight as enhancers for chemiluminescent systems GIRI BRIJ P 2007-11-27 US disclosed
US-20050233303-A1 Polymeric ammonium and or phosphonium salts having added II-electrons and higher molecular weight as enhancers for chemiluminescent systems GIRI BRIJ P 2005-10-20 US disclosed
EP-1534697-A1 POLYMERIC AMMONIUM AND OR PHOSPHONIUM SALTS HAVING ADDED (pgr)-ELECTRONS AND HIGHER MOLECULAR WEIGHT AS ENHANCERS FOR CHEMILUMINESCENT SYSTEMS Giri, Brij P. (US) 2005-06-01 EP disclosed
WO-2003099802-A1 POLYMERIC AMMONIUM AND OR PHOSPHONIUM SALTS HAVING ADDED π-ELECTRONS AND HIGHER MOLECULAR WEIGHT AS ENHANCERS FOR CHEMILUMINESCENT SYSTEMS GIRI BRIJ PAL (US) 2003-12-04 WO disclosed
US-6197594-B1 INCUBATION SAMPLE WITH RECEPTOR WITH CHEMILUMINESCENT LABEL; MEASURING LIGHT EMISION ROCHE DIAGNOSTICS GMBH (DE) 2001-03-06 US disclosed