Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR3 | P25089 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 6/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.37 |
| ▸ | HTR1A | P08908 | 4/20 | 0.37 |
| ▸ | DRD4 | P21917 | 4/20 | 0.37 |
| ▸ | HRH2 | P25021 | 4/20 | 0.37 |
| ▸ | HTR1D | P28221 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 4/20 | 0.37 |
| ▸ | HTR2C | P28335 | 4/20 | 0.37 |
| ▸ | HTR7 | P34969 | 4/20 | 0.37 |
| ▸ | HRH1 | P35367 | 3/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.35 |
| ▸ | DRD1 | P21728 | 3/20 | 0.35 |
| ▸ | DRD5 | P21918 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5499046 | 0.84 | CCR1 (0.38) | DRD2HTR1AHTR2AHTR7HRH1 | |
| SCHEMBL3853355 | 0.80 | DRD2 (0.43) | FPR3FPR2DRD2OPRM1OPRK1 | |
| SCHEMBL3851753 | 0.79 | UBE2M (0.45) | DRD2OPRM1OPRK1HTR1ADRD4 | |
| SCHEMBL2783423 | 0.79 | LMNA (0.44) | DRD2OPRM1OPRK1HTR1ADRD4 | |
| SCHEMBL3853965 | 0.79 | OPRM1 (0.43) | DRD2OPRM1OPRK1HTR1ADRD4 | |
| SCHEMBL2785289 | 0.76 | FFAR4 (0.43) | FPR3FPR2FFAR4HTR2CSLC6A2 | |
| SCHEMBL3772165 | 0.76 | OPRL1 (0.39) | DRD2OPRM1OPRK1CCR1OPRD1 | |
| SCHEMBL3853446 | 0.76 | DRD2 (0.42) | DRD2OPRM1OPRK1HTR1ADRD4 | |
| SCHEMBL3769750 | 0.74 | OPRD1 (0.38) | OPRM1OPRK1OPRD1CYP3A4CYP2D6 | |
| SCHEMBL2783267 | 0.69 | NOTUM (0.41) | FFAR4OPRM1OPRK1OPRD1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765779-A1 | NEW SUBSTITUTED PIPERIDINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2007-03-28 | — | — | EP | disclosed |
| WO-2005121092-A1 | NEW SUBSTITUTED PIPERIDINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2005-12-22 | — | — | WO | disclosed |