Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 0.90 |
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | NPC1 | O15118 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | SCD | O00767 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | AGER | Q15109 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4286191 | 0.95 | ADORA2A (1.00) | ADORA2ARAB9ANPC1SMN1; SMN2SCD | |
| SCHEMBL4290771 | 0.85 | NPC1 (0.79) | ADORA2ARAB9ANPC1SMN1; SMN2SCD | |
| SCHEMBL16378731 | 0.79 | RAB9A (0.73) | ADORA2ARAB9ANPC1SMN1; SMN2SCD | |
| SCHEMBL4884280 | 0.78 | ADORA2A (0.58) | ADORA2ARAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL3194666 | 0.77 | ADORA2A (0.75) | ADORA2ARAB9ANPC1SMN1; SMN2AGER | |
| SCHEMBL3223685 | 0.76 | RAB9A (1.00) | ADORA2ARAB9ANPC1SMN1; SMN2SCD | |
| SCHEMBL995829 | 0.75 | NPC1 (1.00) | RAB9ANPC1SMN1; SMN2SCDLMNA | |
| SCHEMBL14269570 | 0.75 | ADORA2A (0.63) | ADORA2ARAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL8298569 | 0.74 | AGER (0.73) | ADORA2ARAB9ANPC1SMN1; SMN2SCD | |
| Hydrochloric Acid SCHEMBL27594584 | 0.74 | NPC1 (0.97) | RAB9ANPC1SMN1; SMN2SCDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682129-B1 | N-THIAZOL-2-YL-BENZAMIDE DERIVATIVES | LUNDBECK & CO AS H (DK) | 2007-02-21 | — | — | EP | disclosed |
| EP-1682129-A1 | N-THIAZOL-2-YL-BENZAMIDE DERIVATIVES | H. LUNDBECK A/S (DK) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005039572-A1 | N-THIAZOL-2-YL-BENZAMIDE DERIVATIVES | H. LUNDBECK A/S (DK) | 2005-05-06 | — | — | WO | disclosed |