Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | RHEB | Q15382 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505100 | 0.83 | THRA (0.41) | RHEBPPARGPPARDPTGDR2 | |
| SCHEMBL5502760 | 0.77 | MAP2 (0.39) | RHEBALDH1A1MAPTPTGDR2CYP1A2 | |
| SCHEMBL5511414 | 0.74 | TP53 (0.41) | ALDH1A1MAPTGHSRCNR1TP53 | |
| SCHEMBL5501032 | 0.73 | THRA (0.40) | PPARGPPARDALDH1A1GAAMAPT | |
| SCHEMBL5507450 | 0.73 | PTGDR2 (0.40) | RHEBPPARDMAPTCNR1PTGDR2 | |
| SCHEMBL5506365 | 0.73 | LGALS8 (0.41) | RHEBPPARDMRGPRX4CHEK2PTGDR2 | |
| SCHEMBL5506461 | 0.72 | ALOX5 (0.40) | ALDH1A1MAPTTP53CYP1A2CYP2C9 | |
| SCHEMBL5502589 | 0.71 | EGLN1 (0.39) | RHEBPPARGPPARDMAPTHTT | |
| SCHEMBL5517204 | 0.71 | TOP1 (0.34) | PPARDALDH1A1PTGDR2CYP1A2CYP2C9 | |
| SCHEMBL5507821 | 0.71 | ACACB (0.39) | GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841735-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077366-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |