Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | RHEB | Q15382 | 3/20 | 0.38 |
| ▸ | BRAF | P15056 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 3/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5507450 | 0.90 | PTGDR2 (0.40) | THRATHRBPTGDR2RHEBDHODH | |
| SCHEMBL5506365 | 0.89 | LGALS8 (0.41) | THRATHRBPTGDR2RHEBDHODH | |
| SCHEMBL5504469 | 0.84 | PPARD (0.41) | THRBPTGDR2TRPV1EGLN1PPARD | |
| SCHEMBL5501795 | 0.83 | IDO1 (0.36) | PTGDR2RHEBPPARGPPARD | |
| SCHEMBL5502760 | 0.80 | MAP2 (0.39) | PTGDR2RHEBFFAR1 | |
| SCHEMBL5502589 | 0.79 | EGLN1 (0.39) | THRBRHEBFFAR4EGLN1PPARG | |
| SCHEMBL5501032 | 0.79 | THRA (0.40) | THRATHRBFFAR4PPARGPPARD | |
| SCHEMBL5519196 | 0.77 | CSF1R (0.38) | PTGDR2FFAR4FFAR1 | |
| SCHEMBL5507776 | 0.76 | RXRA (0.42) | THRBPPARGPPARDFFAR1 | |
| SCHEMBL5505765 | 0.75 | PTGDR2 (0.44) | THRBPTGDR2PPARDFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841735-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077366-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |