SCHEMBL5502875

SCHEMBL5502875

CC(CCCc1ccccc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.52
KCNH2 Q12809 2/20 0.50
TAAR1 Q96RJ0 2/20 0.48
CHRM2 P08172 1/20 0.47
HTR1A P08908 1/20 0.47
ADRA2A P08913 1/20 0.47
CHRM1 P11229 1/20 0.47
DRD1 P21728 1/20 0.47
SLC6A2 P23975 1/20 0.47
SLC6A4 P31645 1/20 0.47
ADRA1A P35348 1/20 0.47
OPRM1 P35372 1/20 0.47
DRD3 P35462 1/20 0.47
SLC6A3 Q01959 1/20 0.47
SIGMAR1 Q99720 3/20 0.46
EPHX2 P34913 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6282911 0.94 RIPK1 (0.50) RIPK1KCNH2TAAR1SIGMAR1
Bicarbonate SCHEMBL8118714 0.93 EPHX2 (0.51) ADRA1ASLC6A3EPHX2
SCHEMBL6546301 0.89 SMN1; SMN2 (0.47) RIPK1KCNH2TAAR1DRD3
SCHEMBL6547354 0.89 ALDH1A1 (0.48) RIPK1KCNH2SIGMAR1
SCHEMBL11877259 0.87 RIPK1 (0.44) RIPK1KCNH2TAAR1CHRM2HTR1A
SCHEMBL9588733 0.87 SLC6A2 (0.49) RIPK1SLC6A2SLC6A4SLC6A3SIGMAR1
SCHEMBL1324113 0.87 RIPK1 (0.55) RIPK1KCNH2TAAR1SLC6A2SLC6A4
SCHEMBL28012512 0.83 L3MBTL1 (0.54)
SCHEMBL13538390 0.83 SIGMAR1 (0.52) RIPK1TAAR1SIGMAR1
SCHEMBL11158528 0.83 OPRK1 (0.50) KCNH2ADRA2ASLC6A2ADRA1AOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016158679-A1 ENERGY-SENSITIVE RESIN COMPOSITION 東京応化工業株式会社 2016-10-06 WO disclosed
WO-2015198887-A1 ENERGY-SENSITIVE RESIN COMPOSITION 東京応化工業株式会社 2015-12-30 WO disclosed
US-20150337084-A1 METHOD FOR PRODUCING POLYBENZOXAZOLE RESIN TOKYO OHKA KOGYO CO., LTD. (JP) 2015-11-26 US disclosed
EP-2947112-A1 METHOD FOR PRODUCING POLYBENZOXAZOLE RESIN TOKYO OHKA KOGYO CO., LTD. (JP) 2015-11-25 EP disclosed
CN-103459360-B Method for producing 4,4'-diformyldiphenylalkane MITSUBISHI GAS CHEMICAL CO 2015-06-10 CN disclosed
EP-2692717-B1 METHOD FOR PRODUCING 4,4'-DIFORMYLDIPHENYLALKANE MITSUBISHI GAS CHEMICAL CO (JP) 2015-05-13 EP disclosed
US-8969627-B2 Method for producing 4,4'-diformyldiphenylalkane MITSUBISHI GAS CHEMICAL COMPANY, INC (JP) 2015-03-03 US disclosed
EP-2692717-A1 METHOD FOR PRODUCING 4,4'-DIFORMYLDIPHENYLALKANE Mitsubishi Gas Chemical Company, Inc. (JP) 2014-02-05 EP disclosed
CN-102260177-A Propylene glycol derivative, preparation method thereof, pharmaceutical composition thereof and application thereof 2011-11-30 CN disclosed
CN-102260178-A Hydroxyl propanediol derivative, its preparation method, its pharmaceutical composition and its purpose 2011-11-30 CN disclosed
EP-1848692-A1 AZOLYLACYLGUANIDINES AS ß-SECRETASE INHIBITORS Wyeth (US) 2007-10-31 EP disclosed
WO-2006088711-A1 AZOLYLACYLGUANIDINES AS β-SECRETASE INHIBITORS WYETH (US) 2006-08-24 WO disclosed
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed
US-5418256-A Hydrocarbon solvent, degrading and extracting, hydrocarbon reaction products UNIVERSITY OF SOUTH ALABAMA (US) 1995-05-23 US disclosed
US-4584125-A POLYSILOXANE, ORGANIC AMINE OR AMINO-FINCTIONAL ORGANOPOLYSILOXANE, NON-AQUEOUS DISPERSANT, AND FILLER SWS SILICONES CORPORATION (US) 1986-04-22 US disclosed