Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5998058 | 0.98 | ATAD2 (0.45) | ATAD2MAPTLMNAGAAHSD17B10 | |
| SCHEMBL13920385 | 0.79 | TP53 (0.38) | HSD17B10ALDH1A1PDE5AALOX15RAB9A | |
| SCHEMBL5506946 | 0.78 | TRIM24 (0.48) | ATAD2LMNAGAAKMT2AALDH1A1 | |
| SCHEMBL520157 | 0.76 | TRIM24 (0.49) | ATAD2LMNAGAAKMT2AALDH1A1 | |
| Bromide SCHEMBL6853137 | 0.76 | NOTUM (0.50) | MAPTGAAKMT2AMEN1HPGD | |
| SCHEMBL5510757 | 0.74 | BMPR1B (0.48) | ATAD2MAPTLMNAGAAHSD17B10 | |
| SCHEMBL13050813 | 0.74 | NOTUM (0.51) | MAPTGAAKMT2AMEN1HPGD | |
| SCHEMBL5998069 | 0.74 | GAA (0.53) | MAPTLMNAGAACASP1CASP7 | |
| SCHEMBL30661617 | 0.73 | ATAD2 (0.50) | ATAD2MAPTGAAHSD17B10CASP1 | |
| SCHEMBL31419462 | 0.73 | ATAD2 (0.50) | ATAD2MAPTGAAHSD17B10CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781642-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006016221-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-02-16 | — | — | WO | disclosed |