SCHEMBL5503556

SCHEMBL5503556

O=S(=O)(O)c1c[c]c(Cl)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.43
ALDH1A1 P00352 6/20 0.41
TSHR P16473 3/20 0.41
NT5E P21589 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.39
TDP1 Q9NUW8 2/20 0.38
HSD17B10 Q99714 4/20 0.35
KDM4E B2RXH2 2/20 0.35
POLB P06746 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP3A4 P08684 1/20 0.34
MAPK1 P28482 1/20 0.34
CA1 P00915 4/20 0.33
CA2 P00918 4/20 0.33
MMP1 P03956 1/20 0.33
MMP2 P08253 1/20 0.33
MMP9 P14780 1/20 0.33
MMP8 P22894 1/20 0.33
MMP13 P45452 1/20 0.33
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1045428 0.78 ENPP2 (0.41) LMNAALDH1A1CYP3A4MAPK1
SCHEMBL1827674 0.78 CA2 (0.52) ALDH1A1TSHRTDP1CA1CA2
SCHEMBL15653512 0.78 ALDH1A1 (0.46) LMNAALDH1A1TSHRSMN1; SMN2TDP1
SCHEMBL5178148 0.76 LMNA (0.50) LMNAALDH1A1TSHRNT5ESMN1; SMN2
SCHEMBL1376847 0.76 LMNA (0.44) LMNAALDH1A1TSHRNT5ESMN1; SMN2
SCHEMBL8151761 0.76 LMNA (0.44) LMNAALDH1A1TSHRNT5ESMN1; SMN2
SCHEMBL6596907 0.74 LMNA (0.43) LMNAALDH1A1TSHRNT5ESMN1; SMN2
SCHEMBL8901059 0.74 LMNA (0.43) LMNAALDH1A1TSHRNT5ESMN1; SMN2
SCHEMBL6630970 0.74 ALDH1A1 (0.52) LMNAALDH1A1TSHRNT5ESMN1; SMN2
SCHEMBL193305 0.74 ALDH1A1 (0.43) LMNAALDH1A1SMN1; SMN2POLBMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0476928-A1 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1992-03-25 EP claimed
CN-105602279-A Porphyrazine coloring matter, ink composition, recording method, and colored object NIPPON KAYAKU KK 2016-05-25 CN disclosed
CN-105452398-A Ink composition, ink jet recording method using same, and colored material NIPPON KAYAKU KK 2016-03-30 CN disclosed
CN-102558948-B Ink composite, the ink jet recording method using it and record thing SEIKO EPSON CORP. (JP) 2016-02-10 CN disclosed
CN-102395629-B Porphyrazine dye, ink composition containing same, and colored article NIPPON KAYAKU KK 2014-05-14 CN disclosed
CN-101384670-B Porphyrazine dye, ink set, and colored material NIPPON KAYAKU KK 2013-06-05 CN disclosed
CN-101490179-B Disazo pigment composition SUMIKA COLOR KK 2013-05-08 CN disclosed
CN-101298524-B Ink, ink jet recording method, ink cartridge, recording unit, and ink jet recording apparatus CANON KK 2013-03-20 CN disclosed
EP-1354007-B1 SINGLE-PHASE MIXED CRYSTALS OF LAKED MONOAZO DYES CIBA SC HOLDING AG (CH) 2007-02-14 EP disclosed
US-20050227188-A1 Silver halide photosensitive material and method of forming image KONICA MINOLTA PHOTO IMAGINE, INC. (JP) 2005-10-13 US disclosed
EP-0101408-B1 MONOAZO DYESTUFFS, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1986-05-07 EP disclosed
US-4466920-A ANIONIC DYES SANDOZ LTD. (CH) 1984-08-21 US disclosed
EP-0101408-A1 Monoazo dyestuffs, their preparation and their use CIBA-GEIGY AG (CH) 1984-02-22 EP disclosed
US-4366236-A HYDROQUINONE DERIVATIVE LAYER AND A WATER INSOLUBLE POLYMER FUJI PHOTO FILM CO., LTD. (JP) 1982-12-28 US disclosed
US-4185013-A Anionic azo dyes having a 3-dibenzofuranyl diazo component radical optionally having a 2- or 8-sulfo group SANDOZ LTD. (CH) 1980-01-22 US disclosed
US-4125368-A Metallized monoazo dyes TOMS RIVER CHEMICAL CORP. (US) 1978-11-14 US disclosed
US-4081438-A Anionic azo dyes having a 3-dibenzofuranyl diazo component radical optionally having A2-or 8-sulfo group SANDOZ LTD. (CH) 1978-03-28 US disclosed
US-4058515-A Metallized phenyl-azo-naphthol compounds TOMS RIVER CHEMICAL CORPORATION (US) 1977-11-15 US disclosed
US-4055557-A MONOAZO DYES BAYER AKTIENGESELLSCHAFT (DT) 1977-10-25 US disclosed
US-4040840-A MEROCYANINE DYE HAVING ISOXAZOLE NUCLEUS AND PYRAZOLINE-5-ONE NUCLEUSN FUJI PHOTO FILM CO., LTD. (JA) 1977-08-09 US disclosed