SCHEMBL8901059

SCHEMBL8901059

O=S(=O)(O)c1c[c]c(F)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.43
ALDH1A1 P00352 5/20 0.41
TSHR P16473 3/20 0.41
NT5E P21589 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.39
TDP1 Q9NUW8 2/20 0.38
HSD17B10 Q99714 4/20 0.35
KDM4E B2RXH2 2/20 0.35
POLB P06746 1/20 0.35
CYP2D6 P10635 1/20 0.35
CA1 P00915 3/20 0.33
CA2 P00918 3/20 0.33
MMP1 P03956 1/20 0.33
MMP2 P08253 1/20 0.33
MMP9 P14780 1/20 0.33
MMP8 P22894 1/20 0.33
MMP13 P45452 1/20 0.33
PARP1 P09874 1/20 0.33
HPGD P15428 1/20 0.32
NAPRT Q6XQN6 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL150900 0.78 ENPP2 (0.41)
SCHEMBL5178148 0.76 LMNA (0.50) LMNAALDH1A1TSHRNT5ESMN1; SMN2
SCHEMBL8151761 0.76 LMNA (0.44) LMNAALDH1A1TSHRNT5ESMN1; SMN2
SCHEMBL1376847 0.76 LMNA (0.44) LMNAALDH1A1TSHRNT5ESMN1; SMN2
SCHEMBL5503556 0.74 LMNA (0.43) LMNAALDH1A1TSHRNT5ESMN1; SMN2
SCHEMBL6630970 0.74 ALDH1A1 (0.52) LMNAALDH1A1TSHRNT5ESMN1; SMN2
SCHEMBL6596907 0.74 LMNA (0.43) LMNAALDH1A1TSHRNT5ESMN1; SMN2
SCHEMBL6594227 0.71 ALDH1A1 (0.42) LMNAALDH1A1TSHRNT5ESMN1; SMN2
SCHEMBL4904917 0.69 LMNA (0.39) LMNAALDH1A1TSHRNT5ESMN1; SMN2
SCHEMBL150334 0.69 LMNA (0.77) LMNAALDH1A1TSHRNT5ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997019916-A2 BISAZO COMPOUNDS, INTERMEDIATES THEREOF, PROCESS FOR SYNTHESIZING THE SAME AND THERAPEUTIC AGENT FOR VIRAL INFECTION CONTAINING THE SAME FUJI PHOTO FILM CO., LTD. (JP) 1997-06-05 WO disclosed