Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 6/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5506848 | 0.78 | NR3C1 (0.41) | NR3C1NR3C2PGRKDM4EALDH1A1 | |
| SCHEMBL5505984 | 0.75 | SIGMAR1 (0.49) | CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6008635 | 0.71 | GRIA4 (0.40) | ALDH1A1ADRB3 | |
| SCHEMBL10893319 | 0.70 | HTT (0.53) | ADRB3 | |
| SCHEMBL12722551 | 0.68 | KDM4E (0.50) | NR3C1NR3C2PGRKDM4EALDH1A1 | |
| SCHEMBL3640959 | 0.68 | ACACB (0.52) | NR3C1NR3C2PGRKDM4EALDH1A1 | |
| SCHEMBL18292224 | 0.66 | NR3C1 (0.42) | NR3C1NR3C2PGRKDM4EALDH1A1 | |
| SCHEMBL10895597 | 0.66 | ADRB3 (0.49) | ADRB3 | |
| SCHEMBL6008622 | 0.66 | CA1 (0.39) | KDM4EALDH1A1ADRB3 | |
| SCHEMBL3634469 | 0.65 | KDM4E (0.45) | NR3C1NR3C2PGRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828111-A2 | METHODS AND FLUORINATED COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | Neurochem (International) Limited (CH) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006059252-A2 | METHODS AND FLUORINATED COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2006-06-08 | — | — | WO | disclosed |