Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 6/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6008622 | 0.89 | CA1 (0.39) | ALDH1A1CA1CA2CA7CA9 | |
| SCHEMBL5504083 | 0.78 | KEAP1 (0.36) | GRIA4KEAP1NFE2L2ACHEALDH1A1 | |
| SCHEMBL6009060 | 0.75 | KEAP1 (0.37) | GRIA4KEAP1NFE2L2ACHEBCHE | |
| SCHEMBL5503665 | 0.71 | NR3C1 (0.41) | ALDH1A1ADRB3 | |
| SCHEMBL5503668 | 0.69 | CASR (0.39) | ADRB2ADRB1ADRB3SMN1; SMN2 | |
| SCHEMBL5505984 | 0.68 | SIGMAR1 (0.49) | TSHRADRB2 | |
| SCHEMBL6008633 | 0.68 | KCNA5 (0.40) | ALDH1A1TSHRLMNA | |
| SCHEMBL6009992 | 0.67 | HTT (0.35) | ALDH1A1CA1CA2LMNAADRB2 | |
| SCHEMBL6033150 | 0.65 | GABBR2 (0.42) | GRIA4ACHEGBA1BCHEALDH1A1 | |
| SCHEMBL17995187 | 0.64 | KEAP1 (0.39) | KEAP1NFE2L2ACHEALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183800-A1 | Methods and fluorinated compositions for treating amyloid-related diseases | BELLUS HEALTH (INTERNATIONAL) LIMITED (CH) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183800-A1 | Methods and fluorinated compositions for treating amyloid-related diseases | APP, PSEN1, TTR | GRIA4 3357/4885KEAP1 1179/4885NFE2L2 2049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.