Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 3/20 | 0.34 |
| ▸ | DRD3 | P35462 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5503076 | 0.92 | DRD2 (0.38) | DRD2HTR2AHRH1DRD4DRD3 | |
| SCHEMBL5500490 | 0.87 | DRD4 (0.34) | DRD2HTR2AHRH1DRD4DRD3 | |
| SCHEMBL2782274 | 0.84 | DRD2 (0.47) | DRD2HTR2AHRH1DRD4DRD3 | |
| SCHEMBL5509702 | 0.82 | DRD2 (0.37) | DRD2HTR2AHRH1DRD4DRD3 | |
| SCHEMBL2781886 | 0.82 | MAPT (0.41) | DRD2HTR2AHRH1DRD4DRD3 | |
| SCHEMBL2783918 | 0.81 | DRD2 (0.44) | DRD2HTR2AHRH1DRD4DRD3 | |
| SCHEMBL2782501 | 0.80 | HTR1A (0.43) | DRD2HTR2AHRH1DRD4DRD3 | |
| SCHEMBL5505305 | 0.79 | DRD2 (0.37) | DRD2HTR2AHRH1DRD4DRD3 | |
| SCHEMBL2783702 | 0.79 | DRD2 (0.41) | DRD2HTR2AHRH1DRD4DRD3 | |
| SCHEMBL5522908 | 0.79 | DRD4 (0.38) | DRD2HTR2AHRH1DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773772-A1 | NEW DISUBSTITUTED PHENYLPIPERIDINES/PIPERAZINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2007-04-18 | — | — | EP | claimed |
| WO-2005121087-A1 | NEW DISUBSTITUTED PHENYLPIPERIDINES/PIPERAZINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2005-12-22 | — | — | WO | claimed |