Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5509232 | 0.94 | CHRM2 (0.50) | CA12CA1CA2CA4CHRM2 | |
| SCHEMBL6009935 | 0.85 | CHRM2 (0.66) | CA12CA1CA2CA4CHRM2 | |
| SCHEMBL5506845 | 0.84 | HTR6 (0.36) | CA12CA1CA2CA4CHRM2 | |
| SCHEMBL918611 | 0.84 | CA12 (0.50) | CA12CA1CA2CA4TAAR1 | |
| SCHEMBL5503261 | 0.83 | MEN1 (0.47) | KDM4ETAAR1SIGMAR1 | |
| SCHEMBL3136280 | 0.83 | MGLL (0.44) | TAAR1 | |
| SCHEMBL5503782 | 0.82 | NOS1 (0.50) | KDM4ETAAR1 | |
| SCHEMBL3139486 | 0.81 | MGLL (0.51) | CA2TAAR1SCN5A | |
| SCHEMBL5775963 | 0.80 | MEN1 (0.54) | CA12CA1CA2CA4CHRM2 | |
| SCHEMBL778326 | 0.79 | TAAR1 (0.46) | CA12CA1CA2CA4TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828111-A2 | METHODS AND FLUORINATED COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | Neurochem (International) Limited (CH) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006059252-A2 | METHODS AND FLUORINATED COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2006-06-08 | — | — | WO | disclosed |