SCHEMBL778326

SCHEMBL778326

O=S(=O)(O)CCc1ccc(F)cc1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.46
HTR2A P28223 2/20 0.42
KCNH2 Q12809 2/20 0.42
FFAR1 O14842 1/20 0.42
PTGS1 P23219 1/20 0.41
PTGS2 P35354 1/20 0.41
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA4 P22748 1/20 0.41
HTR2C P28335 1/20 0.41
MAOB P27338 1/20 0.41
EGFR P00533 1/20 0.41
ERBB2 P04626 1/20 0.41
CA9 Q16790 1/20 0.41
SLC5A1 P13866 1/20 0.40
SLC5A2 P31639 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL7260125 0.98 TAAR1 (0.45) TAAR1HTR2AKCNH2FFAR1PTGS1
SCHEMBL6579252 0.98 TAAR1 (0.45) TAAR1HTR2AKCNH2FFAR1PTGS1
SCHEMBL3136280 0.88 MGLL (0.44) TAAR1HTR2AKCNH2FFAR1
SCHEMBL3139486 0.86 MGLL (0.51) TAAR1FFAR1CA2
SCHEMBL2441516 0.82 TAAR1 (0.50) TAAR1HTR2AKCNH2CA12CA1
SCHEMBL8145771 0.80 ESR1 (0.56) TAAR1PTGS1PTGS2CA1CA2
SCHEMBL9653975 0.80 RECQL (0.41) PTGS1CA12CA1CA2CA4
SCHEMBL27825383 0.80 TAAR1 (0.48) TAAR1HTR2AKCNH2FFAR1CA12
SCHEMBL29001390 0.80 MGLL (0.48) TAAR1HTR2AKCNH2FFAR1CA12
SCHEMBL5509232 0.79 CHRM2 (0.50) KCNH2CA12CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9216988-B2 Benzyl sulfonamide derivatives as RORc modulators GENENTECH, INC. (US) 2015-12-22 US claimed
US-20250020997-A1 PHOTORESIST COMPOSITIONS AND METHODS OF MANUFACTURING INTEGRATED CIRCUIT DEVICES USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2025-01-16 US disclosed
CN-114105837-B Synthesis and application of alkenyl sulfonyl-containing molecules 中国科学院上海有机化学研究所 2023-05-12 CN disclosed
CN-114105837-A Synthesis and application of molecules containing alkenyl sulfonyl 中国科学院上海有机化学研究所 2022-03-01 CN disclosed
US-9343777-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-05-17 US disclosed
US-9252457-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-02-02 US disclosed
US-9216988-B2 Benzyl sulfonamide derivatives as RORc modulators GENENTECH, INC. (US) 2015-12-22 US disclosed
EP-1676835-B1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT WAKO PURE CHEM IND LTD (JP) 2014-12-10 EP disclosed
US-8669375-B2 Process for producing ester compound WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2014-03-11 US disclosed
US-20130190288-A1 BENZYL SULFONAMIDE DERIVATIVES AS RORC MODULATORS GENENTECH, INC. (US) 2013-07-25 US disclosed
US-7101918-B2 Hybrid type onium salt WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2006-09-05 US disclosed
EP-1690685-A2 Planographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2006-08-16 EP disclosed
EP-1676835-A1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2006-07-05 EP disclosed
US-7049464-B2 Process for producing of an aminoalkylsulfonic acid and a method of salt exchange for a salt thereof WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2006-05-23 US disclosed
US-20050261370-A1 Process for producing of an aminoalkylsulfonic acid and a method of salt exchange for a salt thereof WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2005-11-24 US disclosed
US-20050233253-A1 Diphenylsulfonium compounds in which the S atom is additionally attached to a xanthene-9-onyl-2-yl- or coumarin-7-yl- ring; acid generator for a chemically amplified resist; photopolymerization initiator for polymerizing an epoxide or a vinyl ether WAKO PURE CHEMICAL INDUSTRIES, LTD (JP) 2005-10-20 US disclosed
EP-1548002-A1 PROCESS FOR PRODUCING AMINOALKYLSULFONIC ACID AND METHOD OF SALT EXCHANGE FOR SALT THEREOF Wako Pure Chemical Industries, Ltd. (JP) 2005-06-29 EP disclosed
US-20050020710-A1 Hybrid onium salt WAKO PURE CHEMICALS INDUSTRIES, LTD. (JP) 2005-01-27 US disclosed
EP-1481973-A1 HETEROCYCLE-BEARING ONIUM SALTS Wako Pure Chemical Industries, Ltd. (JP) 2004-12-01 EP disclosed
EP-1443042-A1 HYBRID ONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2004-08-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130190288-A1 BENZYL SULFONAMIDE DERIVATIVES AS RORC MODULATORS RORA, RORC, RORB TAAR1 607/4885HTR2A 2205/4885KCNH2 2718/4885
US-20050233253-A1 Diphenylsulfonium compounds in which the S atom is additionally attached to a xanthene-9-onyl-2-yl- or coumarin-7-yl- ring; acid generator for a chemically amplified resist; photopolymerization initiator for polymerizing an epoxide or a vinyl ether NOX4, CBR1, CBR3 TAAR1 1430/4885HTR2A 4511/4885KCNH2 64/4885
US-20050261370-A1 Process for producing of an aminoalkylsulfonic acid and a method of salt exchange for a salt thereof ARSA, ADSL, ASS1 TAAR1 244/4885HTR2A 2193/4885KCNH2 218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.