Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 11/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL252005 | 0.77 | HSD11B1 (0.42) | HSD11B1ALDH1A1RAB9ALMNATSHR | |
| SCHEMBL1449523 | 0.75 | HSD11B1 (0.49) | HSD11B1ALDH1A1RAB9ALMNATSHR | |
| SCHEMBL1449863 | 0.72 | HPGD (0.58) | HSD11B1ALDH1A1RAB9ATSHRHRH1 | |
| SCHEMBL15170827 | 0.70 | RAB9A (0.38) | HSD11B1ALDH1A1RAB9ALMNATSHR | |
| SCHEMBL15170828 | 0.70 | RAB9A (0.38) | HSD11B1ALDH1A1RAB9ALMNATSHR | |
| SCHEMBL2182851 | 0.69 | DAGLA (0.65) | HSD11B1ALDH1A1 | |
| SCHEMBL5139103 | 0.68 | RAB9A (0.62) | HSD11B1ALDH1A1RAB9ALMNATSHR | |
| SCHEMBL1325460 | 0.68 | RAB9A (0.45) | RAB9ALMNASMN1; SMN2 | |
| SCHEMBL16199152 | 0.67 | RAB9A (0.41) | ALDH1A1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL5592641 | 0.67 | HSD11B1 (0.60) | HSD11B1ALDH1A1RAB9ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1794157-A1 | 2-ACYLAMINOTHIAZOLE DERIVATIVES | H.Lundbeck A/S (DK) | 2007-06-13 | — | — | EP | disclosed |
| WO-2006032273-A1 | 2-ACYLAMINOTHIAZOLE DERIVATIVES | H. LUNDBECK A/S (DK) | 2006-03-30 | — | — | WO | disclosed |