Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 11/20 | 0.42 |
| ▸ | CA1 | P00915 | 10/20 | 0.42 |
| ▸ | CA9 | Q16790 | 10/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 7/20 | 0.39 |
| ▸ | CA4 | P22748 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | CA6 | P23280 | 3/20 | 0.39 |
| ▸ | CA5A | P35218 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.39 |
| ▸ | CA3 | P07451 | 2/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505299 | 0.83 | TSHR (0.39) | LMNACA2CA1MAPTHTT | |
| SCHEMBL4742301 | 0.73 | TRPA1 (0.50) | LMNAMAPTALOX12NPSR1PTGS1 | |
| SCHEMBL31024134 | 0.72 | MEN1 (0.47) | LMNACA2CA1CA9MAPT | |
| SCHEMBL11744639 | 0.72 | NOX1 (0.55) | LMNACA2CA1CA9MAPT | |
| SCHEMBL8131523 | 0.70 | SNCA (0.53) | LMNACA1CA9MAPTHTT | |
| SCHEMBL11120857 | 0.69 | NOX1 (0.46) | MAPTALOX12PTGS1PTGS2 | |
| SCHEMBL8121328 | 0.69 | ACHE (0.50) | LMNAMAPTNPSR1PTGS1 | |
| SCHEMBL11752363 | 0.69 | TRPA1 (0.37) | CA2CA9MAPTALOX12CA12 | |
| SCHEMBL5191452 | 0.69 | CA2 (0.41) | LMNACA2CA1MAPTCA4 | |
| SCHEMBL5191816 | 0.68 | PLEC (0.46) | LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812420-A1 | TRICYCLIC GUANIDINE DERIVATIVES AS SODIUM-PROTON EXCHANGE INHIBITORS | Nicholas Piramal India Limited (IN) | 2007-08-01 | — | — | EP | claimed |
| WO-2006051476-A1 | TRICYCLIC GUANIDINE DERIVATIVES AS SODIUM-PROTON EXCHANGE INHIBITORS | NICHOLAS PIRAMAL INDIA LIMITED (IN) | 2006-05-18 | — | — | WO | claimed |