Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TKT | P29401 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16252213 | 0.79 | SMN1; SMN2 (0.47) | HTTPKMGAASMN1; SMN2MAPT | |
| SCHEMBL17918927 | 0.75 | ATP4A (0.39) | HTTPKMSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL2771532 | 0.75 | RAB9A (0.38) | HTTPKMGAASMN1; SMN2MAPT | |
| SCHEMBL5230966 | 0.70 | SMN1; SMN2 (0.43) | PKMGAASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL13117385 | 0.69 | HTT (0.41) | HTTL3MBTL1PKMSMN1; SMN2PDE3B | |
| SCHEMBL6987692 | 0.67 | RAB9A (0.37) | HTTPKMGAASMN1; SMN2MAPT | |
| SCHEMBL14804204 | 0.67 | TSHR (0.44) | HTTL3MBTL1SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL13841471 | 0.66 | GRM5 (0.36) | HTTSMN1; SMN2ALDH1A1TSHRNPC1 | |
| SCHEMBL14763907 | 0.66 | HCAR2 (0.41) | HTTL3MBTL1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL10754839 | 0.66 | CYP1A2 (0.39) | PKMGAASMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101193891-A | 2-thioethenyl substituted carbapenem derivatives | MEIJI SEIKA KAISHA (JP) | 2008-06-04 | — | — | CN | claimed |
| CN-101193891-A | 2-thioethenyl substituted carbapenem derivatives | MEIJI SEIKA KAISHA (JP) | 2008-06-04 | — | — | CN | disclosed |
| US-20070004700-A1 | 2-Thioethenyl substituted carbapenem derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004700-A1 | 2-Thioethenyl substituted carbapenem derivatives | MTAP, BLVRB, BPGM | HTT 3371/4885L3MBTL1 1129/4885PKM 2870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.