Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | ALDH2 | P05091 | 3/20 | 0.55 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.55 |
| ▸ | CES1 | P23141 | 7/20 | 0.54 |
| ▸ | CDC25A | P30304 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 3/20 | 0.53 |
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29649695 | 0.84 | CES1 (0.71) | MAOAMAOBALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL5114051 | 0.84 | CES1 (0.71) | MAOAMAOBALDH1A1ALDH2ALDH3A1 | |
| Isatin SCHEMBL5510399 | 0.83 | CES1 (0.58) | MAOAMAOBALDH1A1ALDH2ALDH3A1 | |
| Isatin SCHEMBL25225927 | 0.82 | MAOA (0.74) | MAOAMAOBALDH1A1ALDH2ALDH3A1 | |
| Isatin SCHEMBL28796821 | 0.79 | MAOA (0.83) | MAOAMAOBALDH1A1TGM2 | |
| SCHEMBL13299787 | 0.79 | ALDH1A1 (0.45) | ALDH1A1ALDH2ALDH3A1CES1CDC25A | |
| Isatin SCHEMBL5501300 | 0.77 | MAOA (0.57) | MAOAMAOBALDH1A1ALDH2ALDH3A1 | |
| Isatin SCHEMBL29013011 | 0.76 | MAOA (0.77) | MAOAMAOBALDH1A1TGM2PKM | |
| Isatin SCHEMBL973760 | 0.76 | MAOA (1.00) | MAOAMAOBALDH1A1CES1TGM2 | |
| Isatin SCHEMBL34016 | 0.76 | MAOA (1.00) | MAOAMAOBALDH1A1CES1TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781642-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| EP-1781643-A1 | OXINDOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006016220-A1 | OXINDOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-02-16 | — | — | WO | disclosed |
| WO-2006016221-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-02-16 | — | — | WO | disclosed |