SCHEMBL5505977

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5504507	0.87	MEN1 (0.50)	MEN1KMT2AMAPTSMN1; SMN2LMNA
	SCHEMBL8266779	0.85	MAOB (0.44)	MAOBFOSJUNBCHEMEN1
	SCHEMBL6093637	0.84	F3 (0.55)	MEN1KMT2AMAPTSMN1; SMN2LMNA
	SCHEMBL5503711	0.81	ALDH1A1 (0.65)	MAOBBCHEMEN1KMT2ASMN1; SMN2
	SCHEMBL4363448	0.79	MAOB (0.66)	MAOBFOSJUNBCHEMAPT
	SCHEMBL4363444	0.79	MAOB (0.66)	MAOBFOSJUNBCHEMAPT
	SCHEMBL12040547	0.79	GABBR2 (0.53)	MAOBBCHEMEN1KMT2AMAPT
	SCHEMBL6091145	0.79	GABBR2 (0.53)	MAOBBCHEMEN1KMT2AMAPT
	SCHEMBL5510876	0.79	JUN (0.60)	JUNMEN1KMT2AMAPTSMN1; SMN2
	SCHEMBL4728511	0.79	ALDH1A1 (0.61)	MEN1KMT2AMAPTSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.