Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TARDBP | Q13148 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5514123 | 0.93 | KCNH2 (0.55) | KCNH2KDM4ETARDBP | |
| SCHEMBL5512371 | 0.87 | KCNH2 (0.58) | KCNH2KDM4EMCHR1KMT2A | |
| SCHEMBL5508574 | 0.77 | ALDH1A1 (0.47) | MCHR1KMT2A | |
| SCHEMBL5508579 | 0.77 | ALDH1A1 (0.47) | MCHR1KMT2A | |
| SCHEMBL14573144 | 0.76 | KCNH2 (0.61) | KCNH2 | |
| SCHEMBL5509547 | 0.76 | CYP2C9 (0.45) | KCNH2KDM4EKMT2A | |
| SCHEMBL5512152 | 0.75 | KDM4E (0.54) | KDM4ETARDBPMCHR1KMT2A | |
| SCHEMBL5507933 | 0.75 | KCNH2 (0.45) | KCNH2KMT2A | |
| SCHEMBL5764517 | 0.75 | KCNH2 (0.58) | KCNH2 | |
| SCHEMBL14372272 | 0.74 | KCNH2 (0.62) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799676-A2 | NEW BICYCLIC ANTIBIOTICS | Actelion Pharmaceuticals Ltd. (CH) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006032466-A2 | NEW BICYCLIC ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-03-30 | — | — | WO | disclosed |