Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | GCK | P35557 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.35 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.35 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5570207 | 0.84 | GPR35 (0.36) | MCHR1GCKPPARDBRD4PTPN5 | |
| SCHEMBL5573431 | 0.84 | MCHR1 (0.37) | MCHR1GCKPPARDPTPN5ALOX5AP | |
| SCHEMBL5502186 | 0.82 | PTPN11 (0.39) | BTKMCHR1GCKPPARDPTPN11 | |
| SCHEMBL5509633 | 0.82 | DGAT1 (0.35) | MCHR1PPARDPTPN5ALOX5APFEN1 | |
| SCHEMBL5267329 | 0.80 | MCHR1 (0.35) | KMT2AMCHR1PPARDBRD4PTPN5 | |
| SCHEMBL5272120 | 0.80 | MCHR1 (0.34) | KMT2AMCHR1PPARDBRD4PTPN5 | |
| SCHEMBL5509248 | 0.79 | MCL1 (0.40) | GCKPPARDMCL1 | |
| SCHEMBL5574005 | 0.79 | KDM4E (0.43) | KMT2AMCHR1GCKPPARD | |
| SCHEMBL5570203 | 0.79 | KDM4E (0.43) | KMT2AMCHR1GCKPPARD | |
| SCHEMBL5574783 | 0.78 | KDM4E (0.44) | KMT2AMCHR1GCKPPARDBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841735-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077366-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |