Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 12/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5573431 | 0.93 | MCHR1 (0.37) | DGAT1GPR35MCHR1ALOX5APFEN1 | |
| SCHEMBL5570207 | 0.88 | GPR35 (0.36) | DGAT1GPR35MCHR1ALOX5APFEN1 | |
| SCHEMBL5571405 | 0.83 | KDM4E (0.43) | DGAT1MCHR1PPARDCYP1A2 | |
| SCHEMBL5502186 | 0.83 | PTPN11 (0.39) | DGAT1GPR35MCHR1ALOX5APFEN1 | |
| SCHEMBL5509248 | 0.83 | MCL1 (0.40) | DGAT1GPR35PPARDMCL1 | |
| SCHEMBL5267329 | 0.82 | MCHR1 (0.35) | DGAT1MCHR1PTPN5PPARDCYP1A2 | |
| SCHEMBL5272120 | 0.82 | MCHR1 (0.34) | DGAT1MCHR1PTPN5PPARDCYP1A2 | |
| SCHEMBL5506955 | 0.82 | KMT2A (0.39) | MCHR1ALOX5APFEN1PTPN5PPARD | |
| SCHEMBL5574783 | 0.80 | KDM4E (0.44) | DGAT1MCHR1PPARDCYP1A2 | |
| SCHEMBL5574008 | 0.80 | MCHR1 (0.34) | DGAT1GPR35MCHR1PPARDMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841735-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077366-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |