Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10962309 | 0.81 | ADRA2A (0.53) | TAS1R3TAS1R1KDM4EALDH1A1CA12 | |
| SCHEMBL5507364 | 0.78 | RAB9A (0.48) | GPR55TAS1R3TAS1R1KDM4EALDH1A1 | |
| SCHEMBL7922363 | 0.77 | TAS1R3 (0.52) | TAS1R3TAS1R1KDM4EALDH1A1CA12 | |
| SCHEMBL9612683 | 0.77 | TAS1R3 (0.43) | TAS1R3TAS1R1KDM4EALDH1A1CA12 | |
| SCHEMBL11673340 | 0.75 | GPR55 (0.71) | GPR55ACHEKDM4EALDH1A1CA12 | |
| SCHEMBL9593824 | 0.75 | AKR1C3 (0.62) | GPR55TAS1R3TAS1R1KDM4EALDH1A1 | |
| SCHEMBL12072230 | 0.74 | TAS1R3 (0.65) | TAS1R3TAS1R1ALDH1A1BCAT1RAB9A | |
| SCHEMBL12071238 | 0.74 | TAS1R3 (0.65) | TAS1R3TAS1R1ALDH1A1BCAT1RAB9A | |
| SCHEMBL5500520 | 0.74 | PPARG (0.67) | GPR55ACHEKDM4EALDH1A1CA12 | |
| SCHEMBL11247555 | 0.74 | ADRB2 (0.50) | TAS1R3TAS1R1ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070202547-A1 | Methods For Detecting Substances Which Bind To The Amyloid Precursor Protein Or Beta Amyloid Fragments, And Binding Compounds | MERCK & CO., INC. | 2007-08-30 | — | — | US | disclosed |
| US-20070202547-A1 | Methods For Detecting Substances Which Bind To The Amyloid Precursor Protein Or Beta Amyloid Fragments, And Binding Compounds | MERCK & CO., INC. | 2007-08-30 | — | — | US | disclosed |
| US-20070202547-A1 | Methods For Detecting Substances Which Bind To The Amyloid Precursor Protein Or Beta Amyloid Fragments, And Binding Compounds | MERCK & CO., INC. | 2007-08-30 | — | — | US | disclosed |
| EP-1743170-A2 | METHODS FOR DETECTING SUBSTANCES WHICH BIND TO THE AMYLOID PRECURSOR PROTEIN OR BETA AMYLOID FRAGMENTS, AND BINDING COMPOUNDS | Merck & Co., Inc. (US) | 2007-01-17 | — | — | EP | disclosed |
| WO-2005096730-A2 | METHODS FOR DETECTING SUBSTANCES WHICH BIND TO THE AMYLOID PRECURSOR PROTEIN OR BETA AMYLOID FRAGMENTS, AND BINDING COMPOUNDS | MERCK & CO., INC. (US) | 2005-10-20 | — | — | WO | disclosed |