SCHEMBL5507402

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5507986	0.89	THRB (0.59)	HSD17B10ALDH1A1HPGDTP53SMN1; SMN2
	SCHEMBL5508959	0.79	MCL1 (0.62)	HSD17B10KDM4EALDH1A1HPGDTP53
	SCHEMBL5505981	0.78	KDM4E (0.50)	HSD17B10KDM4EALDH1A1HPGDTP53
	SCHEMBL8267145	0.73	SMN1; SMN2 (0.42)	HSD17B10KDM4EALDH1A1HPGDTP53
	SCHEMBL2732524	0.70	KDM4E (0.76)	HSD17B10KDM4EALDH1A1HPGDTP53
	SCHEMBL5507214	0.70	SRD5A2 (0.71)	HSD17B10KDM4EALDH1A1HPGDNPC1
	SCHEMBL7785693	0.70	MAPT (0.63)	ALDH1A1SMN1; SMN2NPC1RAB9AMAPT
	SCHEMBL1753885	0.69	KMT2A (0.81)	HSD17B10KDM4EALDH1A1HPGDSMN1; SMN2
	SCHEMBL2615418	0.69	KMT2A (0.81)	HSD17B10KDM4EALDH1A1HPGDSMN1; SMN2
	SCHEMBL27400764	0.68	MCL1 (0.57)	HSD17B10KDM4EALDH1A1HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.