SCHEMBL5507986

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5507402	0.89	HSD17B10 (0.50)	THRBMAPTPOLBSMN1; SMN2NPC1
	SCHEMBL5504692	0.79	MCL1 (0.64)	THRBMAPTRAB9ATP53HSD17B10
	SCHEMBL5507391	0.77	CLK1 (0.46)	THRBMAPTPOLBSMN1; SMN2RAB9A
	SCHEMBL5509927	0.76	KDM4E (0.66)	THRBMAPTSMN1; SMN2TP53HSD17B10
	SCHEMBL8267145	0.74	SMN1; SMN2 (0.42)	THRBMAPTPOLBSMN1; SMN2TP53
	SCHEMBL15222325	0.72	THRB (0.73)	THRBMAPTPOLBNPC1RAB9A
	SCHEMBL19566616	0.70	TUBB4A (0.50)	THRBMAPTPOLBTP53LMNA
	SCHEMBL5509218	0.69	SRD5A2 (0.73)	SMN1; SMN2NPC1RAB9AHSD17B10TDP1
	SCHEMBL17919672	0.69	TDP1 (0.64)	THRBMAPTPOLBSMN1; SMN2NPC1
	SCHEMBL27400764	0.68	MCL1 (0.57)	THRBMAPTSMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.