Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 13/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5117986 | 0.88 | OPRD1 (0.49) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5121380 | 0.85 | OPRD1 (0.50) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5503244 | 0.84 | KMT2A (0.42) | OPRM1OPRK1 | |
| SCHEMBL5112789 | 0.83 | OPRD1 (0.51) | OPRD1OPRM1OPRK1 | |
| SCHEMBL14000446 | 0.82 | OPRD1 (0.53) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5114230 | 0.80 | OPRD1 (0.52) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5115898 | 0.80 | OPRD1 (0.47) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5511905 | 0.78 | ADRB2 (0.42) | OPRM1OPRK1 | |
| SCHEMBL5504897 | 0.77 | SLC6A12 (0.47) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5126312 | 0.77 | OPRD1 (0.46) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1846400-A2 | TRICYCLIC DELTA-OPIOID MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-10-24 | — | — | EP | disclosed |
| WO-2006074388-A2 | TRICYCLIC δ-OPIOID MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-07-13 | — | — | WO | disclosed |