Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Silicate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Silicate SCHEMBL9450932 | 1.00 | — | — | |
| Silicate SCHEMBL6744995 | 1.00 | — | — | |
| Silicate SCHEMBL5112532 | 0.94 | — | — | |
| Silicate SCHEMBL9794420 | 0.94 | — | — | |
| Silicate SCHEMBL9614709 | 0.94 | — | — | |
| Silicate SCHEMBL6417887 | 0.94 | — | — | |
| Silicate SCHEMBL6014331 | 0.94 | — | — | |
| Silicate SCHEMBL4726242 | 0.94 | — | — | |
| Silicate SCHEMBL14892770 | 0.94 | — | — | |
| Silicate SCHEMBL11706682 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832897-A2 | Hydrated zirconium silicate composition for purification of nucleic acids | Becton, Dickinson and Company (US) | 1998-04-01 | — | — | EP | claimed |
| JP-2075668-A | — | — | None | — | — | JP | disclosed |
| JP-10147592-A | — | — | None | — | — | JP | disclosed |
| JP-10147592-A | — | — | None | — | — | JP | disclosed |
| EP-2891642-B1 | Porous article | SUMITOMO OSAKA CEMENT CO LTD (JP) | 2017-11-08 | — | — | EP | disclosed |
| EP-2818457-B1 | METHOD FOR MANUFACTURING A POROUS ARTICLE | SUMITOMO OSAKA CEMENT CO LTD (JP) | 2017-03-29 | — | — | EP | disclosed |
| US-20150210600-A1 | POROUS ARTICLE AND METHOD OF PRODUCING THE SAME | SUMITOMO OSAKA CEMENT CO., LTD. (JP) | 2015-07-30 | — | — | US | disclosed |
| EP-2891642-A1 | Porous article | Sumitomo Osaka Cement Co., Ltd. (JP) | 2015-07-08 | — | — | EP | disclosed |
| CN-104583156-A | Porous article and method of making same | SUMITOMO OSAKA CEMENT CO LTD | 2015-04-29 | — | — | CN | disclosed |
| EP-2818457-A1 | POROUS ARTICLE, AND METHOD FOR MANUFACTURING SAME | Sumitomo Osaka Cement Co., Ltd. (JP) | 2014-12-31 | — | — | EP | disclosed |
| EP-1242442-B1 | PROCESS FOR THE SCALEABLE PURIFICATION OF PLASMID DNA | MERCK & CO INC (US) | 2007-08-29 | — | — | EP | disclosed |
| EP-0897978-A2 | Zirconium oxide and related compounds for purification of nucleic acids | Becton, Dickinson and Company (US) | 1999-02-24 | — | — | EP | disclosed |
| JP-H10147592-A | HYDRATED ZIRCONIUM SILICATE COMPOSITION FOR PURIFYING NUCLEIC ACID | BECTON DICKINSON & CO | 1998-06-02 | — | — | JP | disclosed |
| JP-H10147592-A | HYDRATED ZIRCONIUM SILICATE COMPOSITION FOR PURIFYING NUCLEIC ACID | BECTON DICKINSON & CO | 1998-06-02 | — | — | JP | disclosed |
| EP-0832897-A3 | Hydrated zirconium silicate composition for purification of nucleic acids | Becton, Dickinson and Company (US) | 1998-05-13 | — | — | EP | disclosed |
| EP-0832897-A3 | Hydrated zirconium silicate composition for purification of nucleic acids | Becton, Dickinson and Company (US) | 1998-05-13 | — | — | EP | disclosed |
| EP-0832897-A2 | Hydrated zirconium silicate composition for purification of nucleic acids | Becton, Dickinson and Company (US) | 1998-04-01 | — | — | EP | disclosed |
| EP-0832897-A2 | Hydrated zirconium silicate composition for purification of nucleic acids | Becton, Dickinson and Company (US) | 1998-04-01 | — | — | EP | disclosed |
| EP-0832897-A2 | Hydrated zirconium silicate composition for purification of nucleic acids | Becton, Dickinson and Company (US) | 1998-04-01 | — | — | EP | disclosed |
| JP-H0275668-A | COATED PIGMENT AND ITS PRODUCTION | KANEBO LTD | 1990-03-15 | — | — | JP | disclosed |