Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMAD3 | P84022 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | GLB1 | P16278 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL500740 | 0.88 | MAPT (0.33) | SMAD3ALDH1A1HPGDBRCA1HSD17B10 | |
| SCHEMBL37698 | 0.85 | HPGD (0.54) | SMAD3ALDH1A1HPGDBRCA1HSD17B10 | |
| SCHEMBL3472516 | 0.78 | THRB (0.44) | SMAD3ALDH1A1HPGDBRCA1HSD17B10 | |
| SCHEMBL7575984 | 0.78 | MAPT (0.60) | SMAD3ALDH1A1HPGDBRCA1HSD17B10 | |
| SCHEMBL1022908 | 0.77 | SMAD3 (0.40) | SMAD3ALDH1A1HPGDBRCA1HSD17B10 | |
| SCHEMBL235829 | 0.77 | SMAD3 (0.40) | SMAD3ALDH1A1HPGDBRCA1HSD17B10 | |
| SCHEMBL29461682 | 0.77 | SMAD3 (0.40) | SMAD3ALDH1A1HPGDBRCA1HSD17B10 | |
| SCHEMBL1468956 | 0.76 | ALDH1A1 (0.40) | SMAD3ALDH1A1HPGDBRCA1HSD17B10 | |
| SCHEMBL9440721 | 0.75 | ALDH1A1 (0.38) | SMAD3ALDH1A1HPGDBRCA1HSD17B10 | |
| Cyanide SCHEMBL6533545 | 0.75 | SMAD3 (0.38) | SMAD3ALDH1A1HPGDBRCA1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802727-A1 | FLUORESCENT DYE COMPOUNDS, CONJUGATES AND USES THEREOF | Applera Corporation (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006034036-A1 | FLUORESCENT DYE COMPOUNDS, CONJUGATES AND USES THEREOF | APPLERA CORPORATION (US) | 2006-03-30 | — | — | WO | disclosed |