Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMAD3 | P84022 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | GLB1 | P16278 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL235829 | 1.00 | SMAD3 (0.40) | SMAD3HPGDALDH1A1HSD17B10BRCA1 | |
| Cyanide SCHEMBL6533545 | 0.97 | SMAD3 (0.38) | SMAD3HPGDALDH1A1HSD17B10BRCA1 | |
| SCHEMBL6045753 | 0.92 | ALDH1A1 (0.47) | SMAD3HPGDALDH1A1HSD17B10BRCA1 | |
| SCHEMBL1022908 | 0.91 | SMAD3 (0.40) | SMAD3HPGDALDH1A1HSD17B10BRCA1 | |
| SCHEMBL6816059 | 0.87 | SMAD3 (0.36) | SMAD3HPGDALDH1A1HSD17B10BRCA1 | |
| SCHEMBL231207 | 0.85 | ALDH1A1 (0.58) | SMAD3HPGDALDH1A1HSD17B10BRCA1 | |
| SCHEMBL5489541 | 0.83 | SMAD3 (0.35) | SMAD3HPGDALDH1A1HSD17B10BRCA1 | |
| SCHEMBL29838734 | 0.83 | SMAD3 (0.35) | SMAD3HPGDALDH1A1HSD17B10BRCA1 | |
| SCHEMBL29838717 | 0.83 | SMAD3 (0.35) | SMAD3HPGDALDH1A1HSD17B10BRCA1 | |
| SCHEMBL1444923 | 0.83 | SMAD3 (0.57) | SMAD3HPGDALDH1A1HSD17B10BRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4653448-A1 | COMPOUND FOR RNA CAPPING AND USE THEREOF | Guangzhou Henovcom Bioscience Co. Ltd. (CN) | 2025-11-26 | — | — | EP | claimed |
| CN-120009524-A | High-flux staphylococcus aureus enterotoxin microfluidic chip detection method based on chain quantity amplification fluorescence enhancement and application | 中国人民解放军军事科学院军事医学研究院 | 2025-05-16 | — | — | CN | claimed |
| WO-2025098478-A1 | WHOLE-PROCESS TARGETING POLYPEPTIDE, PHARMACEUTICAL COMPLEX THEREOF, DRUG DELIVERY SYSTEM AND USE THEREOF | 复旦大学 | 2025-05-15 | — | — | WO | claimed |
| CN-119954892-A | Whole-process targeting polypeptide, drug complex, drug delivery system and application thereof | 复旦大学 | 2025-05-09 | — | — | CN | claimed |
| CN-114981310-B | Application of whole-process targeting molecule and drug complex thereof in construction of drug delivery system | 复旦大学 | 2024-12-03 | — | — | CN | claimed |
| CN-118421832-A | Primer pair and kit for detecting HPV16 and application of primer pair and kit | 北洋酶(天津)生物科技有限公司 | 2024-08-02 | — | — | CN | claimed |
| CN-117987598-A | Primer pair, kit and method for detecting hepatitis E virus | 中国农业大学 | 2024-05-07 | — | — | CN | claimed |
| CN-117925784-A | Enzyme digestion reaction mediated time sequence fluorescence coding high-dimensional imaging tag, probe composition and application thereof | 上海交通大学 | 2024-04-26 | — | — | CN | claimed |
| CN-117925783-A | DNA strand displacement reaction mediated time sequence fluorescent coding high-dimensional imaging tag and application thereof | 上海交通大学 | 2024-04-26 | — | — | CN | claimed |
| CN-116200536-A | Novel method and kit for detecting monkey poxvirus | 中国科学院上海巴斯德研究所 | 2023-06-02 | — | — | CN | claimed |
| CN-114981310-A | Whole-process targeting molecule and application of drug compound thereof in construction of drug delivery system | 复旦大学 | 2022-08-30 | — | — | CN | claimed |
| US-20220193271-A1 | DETECTION OF COLONIC NEOPLASIA IN VIVO USING NEAR-INFRARED PEPTIDE TARGETED AGAINST OVEREXPRESSED CMET | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2022-06-23 | — | — | US | claimed |
| US-12637489-B2 | Silicon containing modified nucleotide analogs | Singular Genomics Systems, Inc. (US) | 2026-05-26 | — | — | US | disclosed |
| US-12630808-B2 | Modified archaeal family b polymerases | Singular Genomics Systems, Inc. (US) | 2026-05-19 | — | — | US | disclosed |
| US-20260125660-A1 | MODIFIED ARCHAEAL FAMILY B POLYMERASES | SINGULAR GENOMICS SYSTEMS INC (US) | 2026-05-07 | — | — | US | disclosed |
| WO-2026090477-A1 | HELICASE INHIBITORS AND USES THEREOF | KIMIA THERAPEUTICS, INC. (US) | 2026-04-30 | — | — | WO | disclosed |
| US-11291174-B2 | Methods for simultaneous pooled genotyping | PIONEER HI-BRED INTERNATIONAL, INC. | 2022-04-05 | — | — | US | disclosed |
| WO-2022048730-A1 | CROSS-LINKABLE COMPOSITIONS BASED ON ORGANOSILICON COMPOUNDS | WACKER CHEMIE AG (DE) | 2022-03-10 | — | — | WO | disclosed |
| US-11266673-B2 | Nucleotide derivatives and methods of use thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-03-08 | — | — | US | disclosed |
| CN-114075593-A | Probe, kit, detection method and application for detecting human RET gene exon 12 | 派德洛格(天津)生物科技有限公司 | 2022-02-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12630808-B2 | Modified archaeal family b polymerases | SSU72, POLB, POLQ | SMAD3 4151/4885HPGD 4147/4885ALDH1A1 2884/4885 |
| US-12637489-B2 | Silicon containing modified nucleotide analogs | NSUN2, POLR2H, POLH | SMAD3 971/4885HPGD 3908/4885ALDH1A1 3879/4885 |
| US-20260125660-A1 | MODIFIED ARCHAEAL FAMILY B POLYMERASES | DNMT3A, POLB, POLM | SMAD3 2652/4885HPGD 2176/4885ALDH1A1 3860/4885 |
| US-11266673-B2 | Nucleotide derivatives and methods of use thereof | POLRMT, NSUN2, NUDT1 | SMAD3 4252/4885HPGD 1426/4885ALDH1A1 955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.