Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMAD3 | P84022 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | GLB1 | P16278 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29461682 | 1.00 | SMAD3 (0.40) | SMAD3HPGDALDH1A1HSD17B10BRCA1 | |
| Cyanide SCHEMBL6533545 | 0.97 | SMAD3 (0.38) | SMAD3HPGDALDH1A1HSD17B10BRCA1 | |
| SCHEMBL6045753 | 0.92 | ALDH1A1 (0.47) | SMAD3HPGDALDH1A1HSD17B10BRCA1 | |
| SCHEMBL1022908 | 0.91 | SMAD3 (0.40) | SMAD3HPGDALDH1A1HSD17B10BRCA1 | |
| SCHEMBL6816059 | 0.87 | SMAD3 (0.36) | SMAD3HPGDALDH1A1HSD17B10BRCA1 | |
| SCHEMBL231207 | 0.85 | ALDH1A1 (0.58) | SMAD3HPGDALDH1A1HSD17B10BRCA1 | |
| SCHEMBL5489541 | 0.83 | SMAD3 (0.35) | SMAD3HPGDALDH1A1HSD17B10BRCA1 | |
| SCHEMBL29838734 | 0.83 | SMAD3 (0.35) | SMAD3HPGDALDH1A1HSD17B10BRCA1 | |
| SCHEMBL29838717 | 0.83 | SMAD3 (0.35) | SMAD3HPGDALDH1A1HSD17B10BRCA1 | |
| SCHEMBL1444923 | 0.83 | SMAD3 (0.57) | SMAD3HPGDALDH1A1HSD17B10BRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1487 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024143925-A1 | ANTIBODY OR PEPTIDE BINDING SPECIFICALLY TO RNASE A, IMMUNOASSAY DEVICE AND METHOD FOR DETECTING RNASE A, AND METHOD FOR COLLECTING RNASE A | 연세대학교 산학협력단 | 2024-07-04 | — | — | WO | claimed |
| US-11906523-B2 | Signaling conjugates and methods of use | VENTANA MEDICAL SYSTEMS, INC. (US) | 2024-02-20 | — | — | US | claimed |
| EP-4279498-A1 | SWITCHING PEPTIDE, IMMUNOASSAY DEVICE COMPRISING SAME, AND IMMUNOASSAY METHOD USING SAME | Optolane Technologies Inc. (KR) | 2023-11-22 | — | — | EP | claimed |
| US-11248260-B2 | Quantitative amplification normalization with quenchers | BIO-RAD LABORATORIES, INC. (US) | 2022-02-15 | — | — | US | claimed |
| EP-3875599-A1 | METHODS FOR DETECTION OF RARE SUBPOPULATIONS OF CELLS AND HIGHLY PURIFIED COMPOSITIONS OF CELLS | Astellas Institute for Regenerative Medicine (US) | 2021-09-08 | — | — | EP | claimed |
| EP-2596119-B1 | METHODS FOR DETECTION OF RARE SUBPOPULATIONS OF CELLS AND HIGHLY PURIFIED COMPOSITIONS OF CELLS | ASTELLAS INST FOR REGENERATIVE MEDICINE (US) | 2021-04-28 | — | — | EP | claimed |
| US-10961342-B2 | Resin formulation and uses thereof | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2021-03-30 | — | — | US | claimed |
| US-10809196-B2 | Quencher containing water soluble polymer-conjugated nanomaterial and use thereof | LEMONEX INC. (KR) | 2020-10-20 | — | — | US | claimed |
| US-20200087443-A1 | A Resin Formulation and Uses Thereof | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2020-03-19 | — | — | US | claimed |
| US-20180306718-A1 | QUENCHER CONTAINING WATER SOLUBLE POLYMER-CONJUGATED NANOMATERIAL AND USE THEREOF | LEMONEX INC. (KR) | 2018-10-25 | — | — | US | claimed |
| EP-0777749-B1 | COUPLED AMPLIFICATION AND LIGATION METHOD | PE CORP NY (US) | 2002-10-30 | — | — | EP | claimed |
| US-20020115067-A1 | Asymmetric benzoxanthene dye labelling reagents | THE PERKIN-ELMER CORPORATION | 2002-08-22 | — | — | US | claimed |
| JP-3102800-B2 | — | — | 2000-10-23 | — | — | JP | claimed |
| US-6130073-A | DETECTING A TARGET NUCLEOTIDE SEQUENCES IN A SAMPLE; AMPLIFYING TARGET NUCLEOTIDE SEQUENCES BY PRIMER EXTENSION, LIGATING OLIGONUCLEOTIDE PROBES AND DETECTING LIGATION PRODUCTS | PERKIN-ELMER CORP., APPLIED BIOSYSTEMS DIVISION (US) | 2000-10-10 | — | — | US | claimed |
| US-6020481-A | FLUORESCENT LABELING REAGENTS; DIDEOXY POLYNUCLEOTIDE SEQUENCING AND FRAGMENT ANALYSIS METHODS. | THE PERKIN-ELMER CORPORATION (US) | 2000-02-01 | — | — | US | claimed |
| EP-0891393-B1 | ASYMMETRIC BENZOXANTHENE DYES | PERKIN ELMER CORP (US) | 1999-06-30 | — | — | EP | claimed |
| US-5912148-A | DETECTION OF POLYNUCLEOTIDE IN SAMPLE BY POLYMERASE CHAIN REACTION AND LIGATION OF OLIGONUCLEOTIDE PROBES WHICH HYBRIDIZE TO AMPLIFICATION PRODUCT, DETECTION OF LIGATION PRODUCT IN ONE REACTION VESSEL | PERKIN-ELMER CORPORATION APPLIED BIOSYSTEMS (US) | 1999-06-15 | — | — | US | claimed |
| WO-1999009212-A1 | TELOMERASE ASSAY | QUEEN MARY & WESTFIELD COLLEGE (GB) | 1999-02-25 | — | — | WO | claimed |
| EP-0777749-A2 | COUPLED AMPLIFICATION AND LIGATION METHOD | PERKIN-ELMER CORPORATION (US) | 1997-06-11 | — | — | EP | claimed |
| WO-1996006190-A2 | COUPLED AMPLIFICATION AND LIGATION METHOD | PERKIN-ELMER CORPORATION (US) | 1996-02-29 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11906523-B2 | Signaling conjugates and methods of use | CABLES1, ILK, BCR | SMAD3 1210/4885HPGD 3734/4885ALDH1A1 1683/4885 |
| US-20020115067-A1 | Asymmetric benzoxanthene dye labelling reagents | POLL, DUT, IPO5 | SMAD3 4294/4885HPGD 3460/4885ALDH1A1 1292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.