Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | NEK1 | Q96PY6 | 13/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5266671 | 0.88 | POLB (0.41) | ALOX5MAP3K5MEN1POLBMAPT | |
| SCHEMBL5506452 | 0.87 | ALDH1A1 (0.48) | ALOX5MAP3K5MEN1POLBMAPT | |
| SCHEMBL5505103 | 0.84 | LMNA (0.39) | ALOX5MAP3K5MEN1MAPTKMT2A | |
| SCHEMBL5501345 | 0.84 | POLB (0.42) | ALOX5MEN1POLBMAPTKMT2A | |
| SCHEMBL5508283 | 0.83 | TP53 (0.42) | ALOX5MEN1POLBMAPTKMT2A | |
| SCHEMBL5512279 | 0.81 | TLR9 (0.38) | ALOX5MAPTSMN1; SMN2TP53MDM2 | |
| SCHEMBL5503574 | 0.80 | MEN1 (0.39) | ALOX5MAP3K5MEN1POLBMAPT | |
| SCHEMBL5507785 | 0.80 | ALOX5 (0.42) | ALOX5MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL334975 | 0.79 | HSD17B10 (0.48) | MEN1POLBMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL5503249 | 0.78 | KDM4E (0.37) | MAP3K5MEN1POLBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841735-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077366-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |