Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5508296 | 1.00 | LMNA (0.43) | LMNAMAPTALDH1A1KMT2ACACNA1C | |
| SCHEMBL2993871 | 0.86 | NR3C2 (0.48) | LMNAMAPTALDH1A1CACNA1CCACNA1F | |
| SCHEMBL2993869 | 0.86 | NR3C2 (0.48) | LMNAMAPTALDH1A1CACNA1CCACNA1F | |
| SCHEMBL5508963 | 0.79 | DRD2 (0.42) | ALDH1A1SLC6A2SLC6A4SLC6A3NPSR1 | |
| SCHEMBL21200226 | 0.77 | SLC9A1 (0.54) | LMNAMAPTALDH1A1KMT2ANPSR1 | |
| SCHEMBL29867155 | 0.77 | SLC9A1 (0.54) | LMNAMAPTALDH1A1KMT2ANPSR1 | |
| SCHEMBL6596250 | 0.77 | ALDH1A1 (0.48) | LMNAMAPTALDH1A1KMT2ANPSR1 | |
| SCHEMBL30879550 | 0.76 | SLC9A1 (0.62) | LMNAMAPTALDH1A1KMT2ACACNA1C | |
| SCHEMBL30879548 | 0.76 | SLC9A1 (0.62) | LMNAMAPTALDH1A1KMT2ACACNA1C | |
| SCHEMBL5780021 | 0.76 | SLC9A1 (0.62) | LMNAMAPTALDH1A1KMT2ACACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856096-A2 | PHENYLGLYCINAMIDE DERIVATIVES USEFUL AS ANTICOAGULANTS | Bristol-Myers Squibb Company (US) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006076246-A2 | PHENYLGLYCINAMIDE DERIVATIVES USEFUL AS ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-07-20 | — | — | WO | disclosed |