Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2913732 | 0.86 | NPC1 (0.41) | DRD2ALDH1A1NPSR1GAAMCHR1 | |
| SCHEMBL2913733 | 0.86 | NPC1 (0.41) | DRD2ALDH1A1NPSR1GAAMCHR1 | |
| SCHEMBL8262944 | 0.85 | DRD2 (0.42) | DRD2SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL5508962 | 0.81 | TSHR (0.41) | SLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL5508296 | 0.79 | LMNA (0.43) | SLC6A2SLC6A4SLC6A3ALDH1A1TSHR | |
| SCHEMBL5508290 | 0.79 | LMNA (0.43) | SLC6A2SLC6A4SLC6A3ALDH1A1TSHR | |
| SCHEMBL13613428 | 0.73 | ALDH1A1 (0.43) | ALDH1A1TSHRHSD17B10CYP1A2 | |
| SCHEMBL2637528 | 0.72 | NPC1 (0.55) | DRD2SCN9AMCHR1 | |
| SCHEMBL22805991 | 0.69 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4399848 | 0.69 | DRD2 (0.59) | DRD2ALDH1A1SCN9AMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856096-A2 | PHENYLGLYCINAMIDE DERIVATIVES USEFUL AS ANTICOAGULANTS | Bristol-Myers Squibb Company (US) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006076246-A2 | PHENYLGLYCINAMIDE DERIVATIVES USEFUL AS ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-07-20 | — | — | WO | disclosed |