Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP5 | P45974 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 2/20 | 0.32 |
| ▸ | CTSC | P53634 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 2/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5519230 | 0.91 | DRD2 (0.38) | USP5LMNAMMP3L3MBTL1 | |
| SCHEMBL2156329 | 0.83 | MMP13 (0.48) | LMNACYP3A4MMP13MMP14 | |
| SCHEMBL2156546 | 0.81 | USP5 (0.38) | USP5LMNASMN1; SMN2CCR5EGFR | |
| SCHEMBL2155739 | 0.80 | MMP13 (0.44) | USP5LMNASMN1; SMN2CCR5CYP3A4 | |
| SCHEMBL2155744 | 0.79 | USP5 (0.40) | USP5LMNASMN1; SMN2CCR5MMP3 | |
| SCHEMBL2156562 | 0.79 | MMP3 (0.40) | USP5LMNASMN1; SMN2CCR5EGFR | |
| SCHEMBL2155796 | 0.79 | MMP13 (0.50) | LMNACYP3A4MMP13MMP14 | |
| SCHEMBL2155603 | 0.79 | HSD17B10 (0.51) | LMNASMN1; SMN2 | |
| SCHEMBL2155666 | 0.76 | KDM4E (0.39) | LMNASMN1; SMN2CYP3A4MMP13MMP14 | |
| SCHEMBL2156070 | 0.75 | POLB (0.40) | LMNASMN1; SMN2CYP3A4MMP13MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828160-A1 | SULFONYL AMINO CYCLIC DERIVATIVES AND USE THEREOF AS MMP INHIBITORS | LABORATOIRES SERONO S.A. (CH) | 2007-09-05 | — | — | EP | claimed |
| WO-2006067114-A1 | SULFONYL AMINO CYCLIC DERIVATIVES AND USE THEREOF | LABORATOIRES SERONO S.A. (CH) | 2006-06-29 | — | — | WO | claimed |