Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | RGS12 | O14924 | 2/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5509080 | 0.76 | PTPN5 (0.37) | MAPTACACBACACALMNAKDM4E | |
| SCHEMBL5505257 | 0.75 | ALDH1A1 (0.39) | MAPTKMT2AGAAACACBACACA | |
| SCHEMBL5518519 | 0.70 | ACACB (0.37) | ACACBACACALMNAPOLB | |
| SCHEMBL5339900 | 0.70 | BRD4 (0.40) | SMN1; SMN2MEN1KMT2AACACBACACA | |
| SCHEMBL335054 | 0.68 | MAPT (0.45) | MAPTSMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL5502096 | 0.67 | BRD4 (0.39) | ACACBACACAHPGDRAB9ALMNA | |
| SCHEMBL11393861 | 0.67 | HSPB1 (0.57) | MAPTSMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL5271009 | 0.67 | BRD4 (0.36) | MAPTMEN1KMT2AACACBACACA | |
| SCHEMBL3051773 | 0.67 | XDH (0.56) | MAPTSMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL1589998 | 0.67 | HSPB1 (0.63) | MAPTSMN1; SMN2MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841735-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077366-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |