Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | FPR1 | P21462 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5524203 | 0.87 | MEN1 (0.41) | POLBKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL5510893 | 0.86 | PPARD (0.39) | POLBGAAKDM4EALDH1A1MAPT | |
| SCHEMBL5506207 | 0.85 | TP53 (0.41) | POLBKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL5503574 | 0.84 | MEN1 (0.39) | POLBGAAKDM4EALDH1A1MAPT | |
| SCHEMBL5270824 | 0.84 | PTPN1 (0.37) | POLBKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL5519196 | 0.84 | CSF1R (0.38) | POLBALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL5516043 | 0.83 | POLB (0.43) | POLBGAAKDM4EALDH1A1MAPT | |
| SCHEMBL5509130 | 0.83 | DHFR (0.38) | POLBGAAKDM4EALDH1A1MAPT | |
| SCHEMBL5503249 | 0.83 | KDM4E (0.37) | POLBGAAKDM4EALDH1A1MAPT | |
| SCHEMBL5501894 | 0.81 | POLB (0.39) | POLBKDM4EALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841735-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077366-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |