Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5510893 | 0.90 | PPARD (0.39) | MAPTALOX5ALDH1A1MEN1KMT2A | |
| SCHEMBL5506207 | 0.89 | TP53 (0.41) | MAPTLMNAALOX5ALDH1A1MEN1 | |
| SCHEMBL5511414 | 0.89 | TP53 (0.41) | MAPTLMNAALOX5ALDH1A1MEN1 | |
| SCHEMBL5270824 | 0.88 | PTPN1 (0.37) | MAPTALOX5ALDH1A1MEN1KMT2A | |
| SCHEMBL5503574 | 0.88 | MEN1 (0.39) | MAPTALOX5ALDH1A1MEN1KMT2A | |
| SCHEMBL5524203 | 0.84 | MEN1 (0.41) | MAPTLMNAALOX5ALDH1A1MEN1 | |
| SCHEMBL5508776 | 0.83 | POLB (0.41) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL5267628 | 0.81 | PPARD (0.39) | MAPTALOX5ALDH1A1MEN1KMT2A | |
| SCHEMBL5501894 | 0.81 | POLB (0.39) | MAPTLMNAALOX5ALDH1A1MEN1 | |
| SCHEMBL5503551 | 0.81 | LMNA (0.39) | MAPTLMNAKDM4ESCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841735-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077366-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |