Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5524203 | 0.87 | MEN1 (0.41) | POLBTDP1KDM4EMAPTMEN1 | |
| SCHEMBL5506207 | 0.83 | TP53 (0.41) | POLBKDM4EMAPTMEN1KMT2A | |
| SCHEMBL5503574 | 0.82 | MEN1 (0.39) | POLBTDP1KDM4EMAP3K5MAPT | |
| SCHEMBL5270824 | 0.82 | PTPN1 (0.37) | POLBTDP1KDM4EMAPTMEN1 | |
| SCHEMBL5509130 | 0.81 | DHFR (0.38) | POLBKDM4EMAPTMEN1KMT2A | |
| SCHEMBL5508776 | 0.81 | POLB (0.41) | POLBTDP1KDM4EMAPTMEN1 | |
| SCHEMBL5267628 | 0.75 | PPARD (0.39) | POLBTDP1MAPTMEN1KMT2A | |
| SCHEMBL5503551 | 0.75 | LMNA (0.39) | KDM4EMAPTLMNAMAPK1HPGD | |
| SCHEMBL5505105 | 0.75 | ALOX5 (0.43) | KDM4EMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5503249 | 0.74 | KDM4E (0.37) | POLBKDM4EMAP3K5MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841735-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077366-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |