Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.39 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.39 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.39 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.39 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.39 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.39 |
| ▸ | CACNG1 | Q06432 | 2/20 | 0.39 |
| ▸ | CACNB2 | Q08289 | 2/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.39 |
| ▸ | CACNA1E | Q15878 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5508776 | 0.87 | POLB (0.41) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL5510893 | 0.87 | PPARD (0.39) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL5501894 | 0.87 | POLB (0.39) | MEN1KMT2APOLBCACNB4CACNA1A | |
| SCHEMBL5506207 | 0.86 | TP53 (0.41) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL5505105 | 0.86 | ALOX5 (0.43) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL5503574 | 0.85 | MEN1 (0.39) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL5270824 | 0.85 | PTPN1 (0.37) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL5509130 | 0.84 | DHFR (0.38) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL5503249 | 0.82 | KDM4E (0.37) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL5516043 | 0.79 | POLB (0.43) | MEN1KMT2APOLBACHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841735-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077366-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |