Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR1F | P30939 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5508963 | 0.81 | DRD2 (0.42) | TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8262944 | 0.68 | DRD2 (0.42) | TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5508811 | 0.67 | SLC6A4 (0.39) | TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5531271 | 0.67 | SLC6A4 (0.38) | TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2944250 | 0.67 | NPC1 (0.52) | — | |
| SCHEMBL4110657 | 0.66 | F7 (0.39) | TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5508290 | 0.64 | LMNA (0.43) | TSHRHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5508296 | 0.64 | LMNA (0.43) | TSHRHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20899353 | 0.63 | AR (0.39) | TSHRSMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4591071 | 0.63 | NPC1 (0.53) | SMN1; SMN2HTR1AKDM4ESLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856096-A2 | PHENYLGLYCINAMIDE DERIVATIVES USEFUL AS ANTICOAGULANTS | Bristol-Myers Squibb Company (US) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006076246-A2 | PHENYLGLYCINAMIDE DERIVATIVES USEFUL AS ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-07-20 | — | — | WO | disclosed |