SCHEMBL5509288

SCHEMBL5509288

CCCC(On1cccc1C(=O)O)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 8/20 0.43
PPARA Q07869 7/20 0.43
POLB P06746 4/20 0.33
TDP1 Q9NUW8 2/20 0.33
APEX1 P27695 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PTGES O14684 1/20 0.32
ALOX5 P09917 1/20 0.32
SLC6A3 Q01959 2/20 0.32
SLC6A2 P23975 1/20 0.32
CHRM1 P11229 1/20 0.32
AKR1A1 P14550 1/20 0.32
CHRM3 P20309 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32
HRH1 P35367 1/20 0.32
DRD3 P35462 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5515555 0.88 SMN1; SMN2 (0.39) PPARGPPARAPOLBTDP1APEX1
SCHEMBL5512362 0.76 GAA (0.38) POLBTDP1APEX1L3MBTL1HTR2A
SCHEMBL23780595 0.76 TDP1 (0.39) POLBTDP1APEX1L3MBTL1HDAC1
SCHEMBL6832383 0.73 LMNA (0.40) POLBTDP1APEX1L3MBTL1HDAC1
SCHEMBL23780602 0.73 L3MBTL1 (0.39) POLBTDP1APEX1L3MBTL1HDAC1
SCHEMBL5512350 0.73 PPARG (0.44) PPARGPPARAPOLBTDP1PTGES
SCHEMBL23780589 0.71 TSHR (0.41) TDP1L3MBTL1MEN1KMT2AALDH1A1
SCHEMBL5512363 0.71 SLC6A3 (0.40) PPARGPPARAPOLBTDP1APEX1
SCHEMBL23780587 0.70 POLB (0.42) POLBTDP1APEX1L3MBTL1HDAC1
SCHEMBL23798638 0.70 TSHR (0.43) TDP1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1470258-B1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2013-08-28 EP disclosed
US-7250456-B2 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2007-07-31 US disclosed
US-20050148702-A1 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2005-07-07 US disclosed
EP-1470258-A1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL Ledertechnik GmbH (DE) 2004-10-27 EP disclosed
WO-2003064707-A1 COMPOSITIONS AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2003-08-07 WO disclosed