Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 9/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | GCK | P35557 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5509248 | 0.84 | MCL1 (0.40) | MCL1DGAT1PPARDGPR35GCK | |
| SCHEMBL5573431 | 0.83 | MCHR1 (0.37) | MCHR1SCN9AMCL1DGAT1PPARD | |
| SCHEMBL5570207 | 0.83 | GPR35 (0.36) | MCHR1MCL1DGAT1PPARDGPR35 | |
| SCHEMBL5509633 | 0.80 | DGAT1 (0.35) | MCHR1MCL1DGAT1PPARDGPR35 | |
| SCHEMBL5571417 | 0.79 | KDM4E (0.43) | SCN9ADGAT1PPARDGCK | |
| SCHEMBL5502186 | 0.78 | PTPN11 (0.39) | MCHR1SCN9ADGAT1PPARDGPR35 | |
| SCHEMBL5267329 | 0.78 | MCHR1 (0.35) | MCHR1SCN9ADGAT1PPARD | |
| SCHEMBL5574783 | 0.77 | KDM4E (0.44) | MCHR1DGAT1PPARDGCK | |
| SCHEMBL5272120 | 0.77 | MCHR1 (0.34) | MCHR1SCN9ADGAT1PPARD | |
| SCHEMBL5506955 | 0.77 | KMT2A (0.39) | MCHR1MCL1PPARDGCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841736-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077367-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |