Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27921259 | 0.75 | TDP1 (0.62) | TDP1ITGB3ITGA2BALDH1A1GBA1 | |
| SCHEMBL22373191 | 0.75 | ITGB3 (0.40) | TDP1ITGB3ITGA2BALDH1A1KMT2A | |
| SCHEMBL22373000 | 0.75 | ADRB2 (0.43) | TDP1ITGB3ITGA2BKMT2AMEN1 | |
| SCHEMBL22374186 | 0.74 | MAPT (0.42) | ITGB3ITGA2BFAAH | |
| Hydrochloric Acid SCHEMBL4072239 | 0.73 | TDP1 (0.50) | TDP1ITGB3ITGA2BHRH1KEAP1 | |
| SCHEMBL22374195 | 0.73 | MAPT (0.44) | ITGB3ITGA2BPRSS1FAAH | |
| SCHEMBL9285630 | 0.72 | KEAP1 (0.48) | TDP1ITGB3ITGA2BALDH1A1L3MBTL1 | |
| SCHEMBL20288253 | 0.72 | HTR2C (0.47) | ITGB3ITGA2BALDH1A1 | |
| SCHEMBL26412465 | 0.71 | HRH1 (0.42) | ALDH1A1KMT2AMEN1LMNACYP2D6 | |
| SCHEMBL22372823 | 0.71 | ITGB3 (0.41) | TDP1ITGB3ITGA2BRECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753752-A1 | HIGHLY SELECTIVE NOVEL AMIDATION METHOD | Takeda Pharmaceutical Company Limited (JP) | 2007-02-21 | — | — | EP | disclosed |
| WO-2005121133-A1 | HIGHLY SELECTIVE NOVEL AMIDATION METHOD | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-12-22 | — | — | WO | disclosed |