Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 8/20 | 0.37 |
| ▸ | MAOA | P21397 | 8/20 | 0.37 |
| ▸ | MAOB | P27338 | 8/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5508054 | 0.91 | GAA (0.40) | GAASMN1; SMN2KDM1AMAOAMAOB | |
| SCHEMBL19817374 | 0.72 | KDM1A (0.38) | KDM1AMAOAMAOBMAPK1 | |
| SCHEMBL8384320 | 0.71 | THRB (0.35) | GAASMN1; SMN2ALDH1A1KDM4EMAPK1 | |
| SCHEMBL32690457 | 0.70 | KDM1A (0.44) | KDM1AMAOAMAOB | |
| SCHEMBL151522 | 0.69 | TSHR (0.41) | GAAALDH1A1MAPK1 | |
| SCHEMBL3797329 | 0.69 | FABP7 (0.33) | KDM1AALDH1A1 | |
| SCHEMBL28279384 | 0.69 | SIGMAR1 (0.41) | GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL10814139 | 0.69 | LMNA (0.45) | GAASMN1; SMN2OPRM1SLC6A4ALDH1A1 | |
| SCHEMBL4558507 | 0.68 | KCNQ3 (0.40) | KDM1AMAPK1 | |
| SCHEMBL10722403 | 0.68 | MAOA (0.42) | KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814866-A2 | GONADOTROPIN RELEASING HORMONE RECEPTOR ANTAGONISTS | Wyeth a Corporation of the State of Delaware (US) | 2007-08-08 | — | — | EP | claimed |
| WO-2006058012-A2 | GONADOTROPIN RELEASING HORMONE RECEPTOR ANTAGONISTS | WYETH (US) | 2006-06-01 | — | — | WO | claimed |