Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | NPY4R | P50391 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19433226 | 0.85 | CA2 (0.42) | TRPV1TSHRCA1CA2MGLL | |
| SCHEMBL15751111 | 0.84 | KIF11 (0.36) | TRPV1LMNATYRALDH1A1HPGD | |
| SCHEMBL3681691 | 0.83 | CA2 (0.45) | TSHRCA1CA2ALDH1A1TDP1 | |
| SCHEMBL1181137 | 0.83 | ENPP2 (0.41) | LMNATYRTSHRCA1CA2 | |
| SCHEMBL54815 | 0.81 | MAPK1 (0.32) | MAPTALDH1A1HPGDNPC1MAPK1 | |
| SCHEMBL117688 | 0.81 | ENPP2 (0.43) | TSHRMAPTMAPK1HIF1AORAI1 | |
| SCHEMBL9903022 | 0.81 | — | — | |
| SCHEMBL3711217 | 0.81 | — | — | |
| SCHEMBL119711 | 0.81 | TRPV6 (0.39) | CA1CA2ALDH1A1MAPK1HIF1A | |
| SCHEMBL366006 | 0.80 | CA1 (0.52) | CA1CA2CA9MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118561818-A | Diaryl substituted 2, 3-indoline compound or medicinal salt thereof, preparation method and application thereof | 河南大学 | 2024-08-30 | — | — | CN | claimed |
| CN-118561818-A | Diaryl substituted 2, 3-indoline compound or medicinal salt thereof, preparation method and application thereof | 河南大学 | 2024-08-30 | — | — | CN | disclosed |
| CN-115160348-B | Method for directly borating aromatic C-H bond without metal catalysis under illumination | 中山大学 | 2024-06-21 | — | — | CN | disclosed |
| US-20220098137-A1 | ARYL COMPOUNDS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME | NEVADA RESEARCH & INNOVATION CORPORATION (US) | 2022-03-31 | — | — | US | disclosed |
| US-11174211-B2 | Aryl compounds and polymers and methods of making and using the same | NEVADA RESEARCH & INNOVATION CORPORATION (US) | 2021-11-16 | — | — | US | disclosed |
| EP-3271346-B1 | ARYL COMPOUNDS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME | UNIV NEVADA RENO (US) | 2021-05-05 | — | — | EP | disclosed |
| US-20200331831-A1 | ARYL COMPOUNDS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, (US) | 2020-10-22 | — | — | US | disclosed |
| US-10550056-B2 | Aryl compounds and polymers and methods of making and using the same | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (US) | 2020-02-04 | — | — | US | disclosed |
| US-20180244596-A1 | ARYL COMPOUNDS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA (US) | 2018-08-30 | — | — | US | disclosed |
| EP-3271346-A1 | ARYL COMPOUNDS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME | Board of Regents of the Nevada System of Higher Education, on Behalf of the University of Nevada, Reno (US) | 2018-01-24 | — | — | EP | disclosed |
| WO-2016149633-A1 | ARYL COMPOUNDS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (US) | 2016-09-22 | — | — | WO | disclosed |
| US-20070040164-A1 | Polymer complex compound and polymer light emitting device using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200331831-A1 | ARYL COMPOUNDS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME | AHR, TYR, PAH | TRPV1 2289/4885LMNA 856/4885TYR 2/4885 |
| US-20220098137-A1 | ARYL COMPOUNDS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME | AHR, TYR, PAH | TRPV1 2289/4885LMNA 856/4885TYR 2/4885 |
| US-20180244596-A1 | ARYL COMPOUNDS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME | AHR, TYR, PAH | TRPV1 2289/4885LMNA 856/4885TYR 2/4885 |
| US-11174211-B2 | Aryl compounds and polymers and methods of making and using the same | AHR, TYR, PAH | TRPV1 2289/4885LMNA 856/4885TYR 2/4885 |
| US-10550056-B2 | Aryl compounds and polymers and methods of making and using the same | AHR, TYR, PAH | TRPV1 2289/4885LMNA 856/4885TYR 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.