Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.38 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.38 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.38 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19433226 | 0.85 | CA2 (0.42) | ENPP2TSHR | |
| SCHEMBL3681691 | 0.83 | CA2 (0.45) | MEN1KMT2AORAI1ORAI2ORAI3 | |
| SCHEMBL1181137 | 0.83 | ENPP2 (0.41) | ENPP2MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL9903022 | 0.81 | — | — | |
| SCHEMBL5510320 | 0.81 | TRPV1 (0.40) | ORAI1ORAI2ORAI3TRPV6MAPT | |
| SCHEMBL54815 | 0.81 | MAPK1 (0.32) | MAPTMAPK1 | |
| SCHEMBL3711217 | 0.81 | — | — | |
| SCHEMBL119711 | 0.81 | TRPV6 (0.39) | ENPP2ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL366006 | 0.80 | CA1 (0.52) | ENPP2MAPK1PDK1PDK2PDK3 | |
| SCHEMBL4592239 | 0.80 | PGR (0.35) | ENPP2ORAI1ORAI2ORAI3TRPV6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116253755-A | Synthesis method of diaryl borate compound | 湖南大学 | 2023-06-13 | — | — | CN | claimed |
| US-20260014125-A1 | BICYCLIC-TYPE MAT2A INHIBITOR AND USE THEREOF | HAIHE BIOPHARMA CO LTD (CN) | 2026-01-15 | — | — | US | disclosed |
| EP-4556475-A1 | BICYCLIC-TYPE MAT2A INHIBITOR AND USE THEREOF | Haihe Biopharma Co., Ltd. (CN) | 2025-05-21 | — | — | EP | disclosed |
| EP-3626241-B1 | DEUTERATED N-BENZENESULFONYLBENZAMIDE COMPOUND FOR INHIBITING BCL-2 PROTEIN AND COMPOSITION AND USE THEREOF | SHENZHEN TARGETRX INC (CN) | 2025-04-23 | — | — | EP | disclosed |
| CN-119403802-A | Di-parallel ring MAT2A inhibitor and application thereof | 上海海和药物研究开发股份有限公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-113851599-B | Organic electroluminescent device and display device comprising same | 烟台显华光电材料研究院有限公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-113725383-B | Organic electroluminescent device and display device comprising same | 烟台显华光电材料研究院有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-117430596-A | Di-parallel ring MAT2A inhibitor and application thereof | 上海海和药物研究开发股份有限公司 | 2024-01-23 | — | — | CN | disclosed |
| WO-2024012507-A1 | BICYCLIC-TYPE MAT2A INHIBITOR AND USE THEREOF | 上海海和药物研究开发股份有限公司 | 2024-01-18 | — | — | WO | disclosed |
| US-11718611-B2 | Benzenesulfonylbenazamide compound for inhibiting BCL-2 protein and composition and use thereof | SHENZHEN TARGETRX, INC. (CN) | 2023-08-08 | — | — | US | disclosed |
| EP-2781519-A1 | NOVEL ANTIVIRAL PYRROLOPYRIDINE DERIVATIVE AND A PRODUCTION METHOD FOR SAME | Korea Research Institute of Chemical Technology (KR) | 2014-09-24 | — | — | EP | disclosed |
| CN-104066732-A | Novel antiviral pyrrolopyridine derivative and a production method for same | KOREA RES INST CHEM TECH | 2014-09-24 | — | — | CN | disclosed |
| US-20140249162-A1 | NOVEL ANTIVIRAL PYRROLOPYRIDINE DERIVATIVES AND METHOD FOR PREPARING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2014-09-04 | — | — | US | disclosed |
| US-20120115724-A1 | METHOD OF CONTROLLING UNDESIRED VEGETATION | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-10 | — | — | US | disclosed |
| EP-2424367-A1 | METHOD OF CONTROLLING UNDESIRED VEGETATION | Syngenta Limited (GB) | 2012-03-07 | — | — | EP | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| CN-101938905-A | Chemical compounds | SYNGENTA LTD | 2011-01-05 | — | — | CN | disclosed |
| WO-2010125332-A1 | METHOD OF CONTROLLING UNDESIRED VEGETATION | SYNGENTA LIMITED (GB) | 2010-11-04 | — | — | WO | disclosed |
| EP-2237669-A2 | CHEMICAL COMPOUNDS | Syngenta Limited (GB) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009081112-A2 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718611-B2 | Benzenesulfonylbenazamide compound for inhibiting BCL-2 protein and composition and use thereof | BCL2, BCL2L1, BCL2L2 | ENPP2 2621/4885MEN1 3979/4885KMT2A 779/4885 |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | ENPP2 3553/4885MEN1 3860/4885KMT2A 2003/4885 |
| US-20260014125-A1 | BICYCLIC-TYPE MAT2A INHIBITOR AND USE THEREOF | MAT2A, MNAT1, MAT1A | ENPP2 2474/4885MEN1 589/4885KMT2A 124/4885 |
| US-20140249162-A1 | NOVEL ANTIVIRAL PYRROLOPYRIDINE DERIVATIVES AND METHOD FOR PREPARING THE SAME | MAVS, IMPDH1, SARS1 | ENPP2 4040/4885MEN1 4611/4885KMT2A 4376/4885 |
| US-20120115724-A1 | METHOD OF CONTROLLING UNDESIRED VEGETATION | TYMS, DHFR, UNG | ENPP2 4085/4885MEN1 4635/4885KMT2A 1950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.