SCHEMBL5510451

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL416748	0.84	MAPT (0.56)	MAPTTP53LMNAALOX5MAOB
	SCHEMBL17953082	0.82	ALDH1A1 (0.50)	MAPTTP53LMNAALOX5MAOB
	SCHEMBL14013658	0.82	ALOX5 (0.59)	MAPTTP53ALOX5MAOBALDH1A1
	SCHEMBL8545651	0.80	MAPT (0.55)	MAPTTP53LMNAALOX5MAOB
	SCHEMBL1758715	0.76	MAPT (0.55)	MAPTTP53LMNAALOX5MAOB
	SCHEMBL5207946	0.73	MAPT (0.49)	MAPTTP53LMNAALOX5MAOB
	SCHEMBL2818307	0.72	CCR2 (0.45)	MAPTTP53LMNAALOX5MAOB
	SCHEMBL28672526	0.72	ALOX5 (0.46)	MAPTTP53LMNAALOX5MAOB
	SCHEMBL14775630	0.71	ALOX5 (0.49)	MAPTTP53LMNAALOX5MAOB
	SCHEMBL28804341	0.70	ALDH1A1 (0.50)	MAPTTP53LMNAALOX5MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.